Semiconductor Sensor Surface Treatment for Residue-Free Analyte Capture

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Solution Overview

Problem

Semiconductor sensor arrays face reduced effectiveness due to altered surface chemistry and residues from manufacturing processes, leading to erroneous data or no data capture of analytes.

Innovation Solution

Applying a surface agent to the sensor surfaces, which includes functional groups reactive with Bronsted base or Lewis acid structures, to modify the surface chemistry and enhance analyte capture.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If semiconductor processing techniques are used to manufacture sensor arrays, then manufacturing precision and productivity are improved, but surface chemistry is altered and residues are left that reduce sensor effectiveness

Engineering Contradiction:
Improvesensor array fabrication precisionVSAvoidanalyte capture effectiveness
Core Design Contradiction:
Manufacturing precisionVSReliability

Solution Approach 1:

The patent applies surface treatment processes (such as plasma treatment, chemical etching, or coating with specific molecules) to sensor surfaces before the actual sensing operation. This preliminary action removes manufacturing residues and modifies surface chemistry to enhance analyte capture, thereby resolving the contradiction between manufacturing precision and sensor reliability.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent changes surface parameters (such as surface charge, hydrophobicity, or chemical composition) through treatment processes like plasma exposure, chemical immersion, or molecular layer deposition. These parameter changes restore or enhance surface properties affected by manufacturing, improving analyte capture effectiveness without compromising manufacturing precision.

Inventive Principle:
Principle #35Parameter changes

2Reliability

If surface treatment is applied to sensor surfaces, then analyte capture is enhanced and signal quality improves, but additional processing steps are required

Engineering Contradiction:
Improvesignal qualityVSAvoidprocessing steps
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent combines surface treatment steps with existing manufacturing or initialization processes. For example, surface activation is performed during the same processing run as sensor assembly, or coating applications are integrated into standard fabrication sequences. This merging reduces the number of separate processing steps while maintaining signal quality improvements.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent employs self-assembling molecular layers or self-cleaning surface treatments that automatically restore surface properties without requiring complex external processing equipment. The sensor surfaces treat themselves through spontaneous chemical reactions or adsorption processes, reducing device complexity while enhancing reliability.

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The surface treatment improves signal quality and response speed of semiconductor sensors by reducing buffering effects and enhancing analyte capture, resulting in higher signal output and faster reaction kinetics.

Implementation Method 1

A surface agent can bind to a sensor surface. The surface agent can include a functional group reactive with Bronsted base structures or Lewis acid structures on the sensor surface

Methodology Applied
Scientific EffectChemical bonding: Chemical Bonding

Data Source

PatentUS12399148B2Surface treatment of semiconductor sensors
Publication Date: 2025.08.26 LIFE TECHNOLOGIES CORP
  • US12399148B2 patent drawing
  • US12399148B2 patent drawing
  • US12399148B2 patent drawing

AI summary

A sensor component includes a sensor including a sensor surface and a reaction site in cooperation with the sensor and exposing the sensor surface. The reaction site including a reaction site surface. A surface agent is bound to the reaction site surface or the sensor surface. The surface agent includes a surface active functional group reactive with Bronsted base or Lewis acid functionality on the reaction site surface or the sensor surface and including distal functionality that does not have a donor electron pair.