Electrochemical Sensor Admittance Ratio for Geometry Deviation Detection

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Solution Overview

Problem

Existing electrochemical sensor systems face challenges in reliably detecting deviations in the geometry of the detection zone and electrode surfaces, leading to incorrect measurements due to manufacturing errors, mechanical or thermal stress, and changes in the measurement conditions, which are not effectively addressed by current methods.

Innovation Solution

A method using alternating current to measure the conductivity between pairs of electrodes, forming a ratio of apparent conductance values to normalize and evaluate the electrochemically active surface area, allowing for the detection of deviations and prevention of incorrect measurements.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If the actual measurement procedure is used as a control to detect sensor errors, then manufacturing errors and insufficient electrode coverage can be detected, but the detection time is delayed and identical errors in both channels are not detected

Engineering Contradiction:
Improvesensor error detectionVSAvoiddetection time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The invention applies a preliminary control measurement procedure before the actual measurement to detect sensor errors in advance. This preliminary check uses specific control measurements (such as measuring the same sample on both channels simultaneously or using reference measurements) to identify manufacturing errors, electrode coverage issues, or identical errors in both channels before they affect the actual diagnostic measurement, thereby enabling early detection without delaying the diagnostic process.

Inventive Principle:
Principle #10Preliminary action

2Ease of manufacture

If adhesive or welding processes are used to bond plastic materials during test carrier production, then cost-effective manufacturing is achieved, but geometry deviations in the detection zone occur

Engineering Contradiction:
Improveproduction costVSAvoiddetection zone geometry
Core Design Contradiction:
Ease of manufactureVSManufacturing precision

Solution Approach 1:

The invention implements preliminary control measurements during or after the manufacturing process to detect geometry deviations in the detection zone before the test carriers are put into service. These control measurements verify that the adhesive or welding processes have not caused unacceptable geometry deviations, allowing for early identification and rejection of defective test carriers while maintaining cost-effective manufacturing processes.

Inventive Principle:
Principle #10Preliminary action

3Ease of operation

If the measuring chamber is filled with sample liquid to enable measurement, then the electrochemical measurement can be performed, but changes in wetted surface area affect measurement accuracy

Engineering Contradiction:
Improvemeasurement capabilityVSAvoidmeasurement accuracy
Core Design Contradiction:
Ease of operationVSMeasurement precision

Solution Approach 1:

The invention compensates for changes in wetted surface area by using control measurements that are processed together with the actual measurement. The control measurements provide reference data that allows for mathematical compensation or normalization of the actual measurement results, correcting for variations in wetted surface area caused by incomplete filling, air bubbles, or leaky measuring chambers while maintaining the ease of operation of the measurement process.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enables reliable detection of faulty electrodes and measurement conditions, preventing incorrect measurements by normalizing conductivity values and accounting for changes in the wetted surface area, thus ensuring accurate results.

Implementation Method 1

a first admittance value (apparent conductance) is determined between two electrodes (which should be referred to as the first pair of electrodes). Simultaneously or subsequently, a second apparent conductance between two electrodes (which should be referred to as the second pair of electrodes) of the sensor is determined

Methodology Applied
Scientific EffectElectrical conductance measurement: Conduction (electrical)

Implementation Method 2

a liquid measuring medium is first supplied to the sensor. For this liquid transport, capillaries can be used, for example

Methodology Applied
Scientific EffectIonic conduction: Conduction (electrical)

Data Source

PatentEP1772728B1Method and system for testing electrochemical sensors
Publication Date: 2014.01.15 ROCHE DIAGNOSTICS GMBH
  • EP1772728B1 patent drawingFigure 1A~1F
  • EP1772728B1 patent drawingFigure 2~3
  • EP1772728B1 patent drawingFigure 4~5

AI summary

The invention relates to a method and a corresponding system for checking electrochemical sensors with at least two electrodes, wherein i) a liquid measuring medium is first supplied to the sensor; ii) a first apparent conductance (admittance) between two electrodes of the sensor is determined; iii) a second apparent conductance (admittance) between two electrodes of the sensor is determined, and iv) the first and the second apparent conductance are related to each other.