Sensor-Integrated Dialysis Apparatus for Real-Time Parameter Adjustment

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Solution Overview

Problem

Current dialysis machines, particularly peritoneal dialysis machines, operate with fixed treatment protocols and lack real-time monitoring and adjustment capabilities, leading to suboptimal treatment efficiency and comfort, with unused dialysis fluid not being analyzed and treatment parameters not being dynamically adjusted.

Innovation Solution

Integration of sensors within disposable components such as containers, tubing sets, and patient catheters to measure and transmit real-time parameters like urea concentration, pressure, and glucose content, allowing for continuous monitoring and adjustment of treatment parameters during or after the procedure.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If fixed treatment protocols are used in dialysis machines, then the device complexity is reduced and ease of operation is improved, but treatment efficiency and adaptability to patient-specific needs deteriorate

Engineering Contradiction:
Improveease of operationVSAvoidadaptability
Core Design Contradiction:
Ease of operationVSAdaptability or versatility

Solution Approach 1:

The patent implements dynamic treatment protocols that automatically adjust dialysis parameters (flow rates, concentrations, timing) based on real-time sensor measurements of patient-specific parameters such as urea concentration and fluid composition. This transforms the static fixed protocols into adaptive dynamic systems that respond to changing patient conditions during treatment.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system incorporates continuous feedback loops where sensors measure dialysis fluid composition and patient parameters, the control unit processes this data, and the treatment parameters are automatically adjusted accordingly. This closed-loop feedback mechanism enables real-time optimization of treatment efficiency while maintaining ease of operation through automation.

Inventive Principle:
Principle #23Feedback

2Measurement precision

If sensors are integrated into disposable components like containers and tubing sets, then measurement precision and treatment monitoring are improved, but device complexity and manufacturing complexity increase

Engineering Contradiction:
Improvemeasurement precisionVSAvoidease of manufacture
Core Design Contradiction:
Measurement precisionVSEase of manufacture

Solution Approach 1:

The patent integrates sensors directly into disposable components (containers, tubing sets, catheters) that are discarded after single use. This approach accepts increased manufacturing complexity for individual components but eliminates the need for cleaning, sterilization, and maintenance of sensitive sensors, thereby simplifying overall system operation and ensuring measurement precision for each new disposable unit.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Solution Approach 2:

By extracting the sensor integration from permanent machine components and placing it in disposable consumables, the patent separates the complex sensing function from the durable equipment. This allows the main dialysis machine to remain simpler while the disposable components carry the measurement functionality, optimizing the division of complexity.

Inventive Principle:
Principle #2Taking out (Extraction)

3Productivity

If real-time monitoring and adjustment capabilities are added to dialysis machines, then treatment efficiency and patient comfort are improved, but device complexity and energy consumption increase

Engineering Contradiction:
Improvetreatment efficiencyVSAvoiddevice complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent employs multi-functional sensor systems that simultaneously measure multiple parameters (urea concentration, glucose levels, fluid composition, flow rates) using integrated sensor arrays. This universal sensing approach consolidates multiple measurement functions into single components, reducing overall device complexity while enabling comprehensive real-time monitoring and adjustment of treatment parameters.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The system implements self-adjusting capabilities where the control unit automatically modifies treatment parameters based on sensor feedback without requiring constant operator intervention. This self-service automation improves treatment efficiency by continuously optimizing parameters while reducing the operational burden on healthcare providers, offsetting the increased device complexity through intelligence.

Inventive Principle:
Principle #25Self-service

4Reliability

If sensors are placed in disposable components, then reliability and measurement accuracy are improved, but loss of substance and waste increase due to frequent disposal

Engineering Contradiction:
ImprovereliabilityVSAvoidloss of substance
Core Design Contradiction:
ReliabilityVSLoss of substance

Solution Approach 1:

The patent accepts the substitution of permanent reusable components with disposable single-use components containing integrated sensors. While this increases waste and substance loss, it ensures high reliability and measurement accuracy by eliminating contamination risks, sensor drift, and sterilization requirements. The disposable nature guarantees each sensor starts with optimal performance characteristics.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Solution Approach 2:

The system is designed to efficiently utilize the disposable components throughout the treatment process, extracting maximum value from each sensor before disposal. The control unit optimizes sensor usage to ensure accurate measurements are obtained for the entire treatment duration, minimizing waste by fully utilizing each disposable component's measurement capacity.

Inventive Principle:
Principle #34Discarding and recovering

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables real-time monitoring and adjustment of dialysis treatment parameters, improving treatment efficiency and comfort by allowing for dynamic changes based on patient-specific needs, enhancing the detection of treatment success and potential issues like peritonitis, and facilitating more effective and gentle therapy.

Implementation Method 1

The sensors used for this are, for example, conductivity sensors.

Methodology Applied
Scientific EffectConductivity sensing: Conduction (electrical)

Data Source

PatentEP3383451B1Dialysis apparatus
Publication Date: 2021.04.28 FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
  • EP3383451B1 patent drawingFigure 1~2
  • EP3383451B1 patent drawingFigure 3

AI summary

The invention relate to a dialysis apparatus, in particular peritoneal dialysis apparatus, having one or more of the following components: at least one container (20), in particular a bag, to receive fresh or used dialysis fluid, at least one tube set (10) for carrying a liquid, in particular dialysis liquid, at least one patient catheter for introducing and/or discharging dialysis liquid into and out of the abdominal cavity of the patient, wherein at least one of the components has at least one sensor (30), which is designed to measure at least one parameter value of the liquid, and which is also designed to transmit the parameter value to at least one receiver.