Sepsis Condition Classification Using CRT and Vasodilation Data

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Solution Overview

Problem

Existing technologies face challenges in accurately classifying the condition of a subject related to sepsis, particularly in distinguishing between non-shock and warm shock states, due to minimal differences in capillary refill time (CRT) during the early stages of sepsis.

Innovation Solution

A condition classifying device that receives data on blood refilling state after ischemia and physiological parameters affected by vasodilation, using a processor to classify the subject's condition based on both types of data, thereby enhancing classification accuracy.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If only blood refilling state after ischemia (CRT) is used for classification, then the measurement is simple, but the classification accuracy in early stage sepsis is poor

Engineering Contradiction:
Improveclassification accuracyVSAvoiddata collection complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent combines multiple physiological parameters (blood refilling state after ischemia/CRT, physiological parameters affected by vasodilation, and level of consciousness) into a comprehensive classification system. This merging of multiple data sources enables accurate detection of warm shock state in early stage sepsis, resolving the contradiction between measurement simplicity and classification accuracy.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent transitions from single-parameter (CRT only) assessment to multi-dimensional assessment by incorporating physiological parameters affected by vasodilation and level of consciousness. This dimensional expansion provides additional discrimination capability to distinguish warm shock state from non-shock state, improving classification accuracy without excessive complexity increase.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Reliability

If only CRT is monitored, then the system is simple, but the ability to detect warm shock state at early stage is insufficient

Engineering Contradiction:
Improvedetection reliabilityVSAvoidmonitoring system complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent merges CRT monitoring with physiological parameter monitoring affected by vasodilation and level of consciousness assessment. This combination provides reliable detection of warm shock state through complementary information from multiple sources, improving detection reliability while managing system complexity through integrated monitoring.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The system continuously monitors multiple physiological parameters and provides feedback for classification determination. The processor analyzes changes in physiological parameters affected by vasodilation and level of consciousness alongside CRT to dynamically classify the shock state, enhancing reliability through continuous multi-parameter feedback assessment.

Inventive Principle:
Principle #23Feedback

3Measurement precision

If multiple physiological parameters are collected, then the classification accuracy improves, but the data processing complexity increases

Engineering Contradiction:
Improveclassification accuracyVSAvoiddata processing difficulty
Core Design Contradiction:
Measurement precisionVSDifficulty of detecting and measuring

Solution Approach 1:

The patent segments the data processing into distinct functional components: collecting CRT data, collecting physiological parameter data affected by vasodilation, collecting level of consciousness data, and processing these segmented data streams separately before integration for classification. This segmentation reduces overall processing difficulty by handling each parameter type systematically.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The processor is designed with multi-functionality to handle different types of physiological data (CRT, vasodilation effects, consciousness levels) through a unified classification framework. This universal processing approach improves classification accuracy while managing data processing complexity through a single integrated algorithm that handles multiple parameter types.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Data Source

PatentUS12239452B2Device for classifying condition of subject and non-transitory computer-readable medium having recorded computer program for the device
Publication Date: 2025.03.04 NIHON KOHDEN CORP
  • US12239452B2 patent drawing
  • US12239452B2 patent drawing
  • US12239452B2 patent drawing

AI summary

A condition classifying device includes: an input interface configured to receive first data corresponding to a blood refilling state after ischemia of a subject, and second data corresponding to a physiological parameter that exhibits changes caused by vasodilation of the subject; a processor configured to perform a classification of a condition of the subject related to sepsis based on the first data and the second data; and an output interface configured to output a result of the classification.