Sequencing Chip Loading Control at Interruptible Project Nodes
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Solution Overview
Problem
Existing automated nucleic acid sequencing platforms face challenges in accommodating larger numbers of solid substrates while maintaining detection precision and efficiency, as increasing the number of signal detection modules or substrates without significantly increasing volume and weight is difficult, affecting overall operating efficiency and flexibility.
Innovation Solution
A method and apparatus for controlling chip loading that allows flexible loading and unloading of chips based on project type and process state, enabling parallel execution of projects by identifying interruptible nodes and interference-permissible states to manage chip operations without disrupting ongoing processes.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If the number of solid substrates or designated surfaces is increased to increase throughput, then the amount of sequencing data increases, but the volume and weight of the sequencing platform significantly increase
Solution Approach 1:
The system dynamically manages chip loading and unloading based on project execution state. The control method monitors whether additional chips can be loaded without interfering with ongoing projects on other chips, enabling flexible adaptation of platform capacity without permanent structural expansion
Solution Approach 2:
The system performs preliminary monitoring of project execution states before allowing chip loading. By checking whether interruptible nodes have been reached and whether the additional chip is in an interference-permissible state, the system prepares the platform to accommodate more chips without compromising existing operations
2Productivity
If the number of solid substrates or designated surfaces is increased to increase throughput, then the amount of sequencing data increases, but the operating efficiency and flexibility of the platform deteriorate
Solution Approach 1:
The control method implements continuous feedback monitoring of project execution states on all chips. The system tracks whether interruptible nodes have been reached and whether loading additional chips would cause interference, using this feedback to make real-time decisions about chip loading that maintain operating efficiency
Solution Approach 2:
The system dynamically adjusts chip loading decisions based on real-time monitoring of project states. By making the chip loading process adaptive rather than static, the system maintains flexibility and operating efficiency even as throughput increases through multiple chips
3Speed
If chip loading is performed without monitoring project process state, then loading speed increases, but project execution reliability deteriorates due to potential interference
Solution Approach 1:
The system performs preliminary checks of the additional chip's project execution state before allowing loading. By monitoring whether interruptible nodes have been reached and whether the system is in an interference-permissible state, the system ensures reliable project execution while maintaining efficient loading processes
Solution Approach 2:
The control method acts as an intermediary between chip loading operations and project execution processes. It mediates by monitoring project states and determining whether loading conditions are met, ensuring that loading operations do not interfere with ongoing projects while maintaining efficient throughput
Data Source
AI summary
A method and apparatus for controlling chip loading, a sequencing system, and a storage medium. When a current chip needs to be loaded, it is detected that another chip is executing a project, then if another chip is in an interference state and there is an unreached interruptible node, the execution situation of the project process of another chip is monitored; when the loading of the current chip has not been ended, it is detected that another chip has reached the interruptible node, and then another chip is caused to enter a safe mode until the loading of the current chip is ended; and the current chip executes a requested project, and another chip continues executing the interrupted project. Thus, another chip that is executing a project is caused to enter a safe mode at an appropriate time, other chips can be loaded flexibly, and multiple chips are loaded at different times and operate together, thereby improving the operation efficiency and industrial practicability of a detection system.