Double-Layer Vibration Isolation for Sequencing Imaging Modules

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Solution Overview

Problem

Mechanical vibration poses a significant challenge in detection systems and sequencing systems, particularly affecting imaging modules that are sensitive to external and internal vibrations, leading to inaccurate and unreliable sequencing results.

Innovation Solution

A vibration damping structure with a double-layer body design, comprising an upper and lower structure connected by an intermediate structure, with a natural frequency greater than or equal to √{square root over (2)} times the internal excitation frequency, effectively suppresses vibrations in both two-dimensional and three-dimensional movements.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If the imaging module is used to capture signals from nucleic acid molecules, then detection capability is improved, but sensitivity to vibration increases leading to inaccurate sequencing results

Engineering Contradiction:
Improvedetection capabilityVSAvoidsequencing result accuracy
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The body is divided into an upper structure and a lower structure as separate segments, connected through intermediate structures. This segmentation allows independent vibration control of each segment, enabling the upper structure to be isolated from vibrations generated by the lower structure's movement, thereby improving sequencing accuracy while maintaining detection capability

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Intermediate structures serve as mediators between the upper and lower structures. These intermediates include vibration damping components that filter and reduce vibration transmission, allowing the imaging module on the upper structure to capture clear images of nucleic acid molecules without interference from vibrations generated by the lower structure's two-dimensional movement

Inventive Principle:
Principle #24Intermediary (Mediator)

2Device complexity

If a single-layer body structure is used, then device complexity is reduced, but vibration damping effect is insufficient

Engineering Contradiction:
Improvestructure simplicityVSAvoidvibration interference
Core Design Contradiction:
Device complexityVSObject-affected harmful factors

Solution Approach 1:

The design transitions from a single-layer structure to a double-layer structure with upper and lower bodies separated in the vertical dimension. This dimensional change creates space for intermediate vibration damping structures, enabling effective vibration isolation while maintaining relatively simple overall device architecture

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Solution Approach 2:

The vibration damping structure employs composite construction with upper and lower structural layers connected by intermediate damping elements. This composite approach combines rigid structural components with vibration-absorbing materials, achieving effective vibration damping without significantly increasing device complexity

Inventive Principle:
Principle #40Composite materials

3Stability of the object's composition

If the natural frequency of the body is close to the internal excitation frequency, then resonance occurs amplifying vibration, but increasing natural frequency requires structural modification

Engineering Contradiction:
Improvevibration stabilityVSAvoidstructural modification
Core Design Contradiction:
Stability of the object's compositionVSDevice complexity

Solution Approach 1:

The design changes the natural frequency parameter of the body by modifying the structural configuration to a double-layer system with intermediate damping elements. This parameter change ensures the natural frequency is greater than or equal to √2 times the internal excitation frequency, avoiding resonance and reducing vibration amplification while maintaining structural feasibility

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The vibration damping structure significantly enhances the ability to isolate and attenuate external and internal vibrations, improving the accuracy and reliability of imaging and sequencing by maintaining clear images of nucleic acid molecules.

Implementation Method 1

a natural frequency of the body is greater than or equal to √{square root over (2)} times an internal excitation frequency

Methodology Applied
Scientific EffectVibration damping through frequency relationship: Damping

Implementation Method 2

effectively suppress the vibration of the whole platform

Methodology Applied
Scientific EffectVibration suppression: Vibration

Data Source

PatentUS12393009B2Vibration dampening structure, detection system and sequencing system
Publication Date: 2025.08.19 GENEMIND BIOSCIENCES CO LTD
  • US12393009B2 patent drawing
  • US12393009B2 patent drawing
  • US12393009B2 patent drawing

AI summary

A vibration damping structure (60), a detection system and a sequencing system. The vibration damping structure (60) is used in the detection system. The vibration damping structure (60) comprises a main body (62) and a support body (64), the main body (62) is connected to the detection system by means of the support body (64), the main body (62) comprises an imaging module (10), an upper layer structure (66), a lower layer structure (68) and an intermediate structure (70), the imaging module (10) is mounted on the upper layer structure (66), the lower layer structure (68) bears the upper layer structure (66) by means of the intermediate structure (70), and the natural frequency of the main body (62) is greater than or equal to √{square root over (2)} times the internal excitation frequency.