Sequencing Imaging Mount With Dual-Layer Vibration Isolation

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Solution Overview

Problem

Mechanical vibration poses a significant challenge in sequencing systems, particularly affecting the imaging module's ability to capture clear images of nucleic acid molecules, leading to inaccurate sequencing results due to external and internal excitation.

Innovation Solution

A vibration damping structure with a double-layer body design, comprising an upper structure, lower structure, and intermediate structure, with a natural frequency greater than twice the internal excitation frequency, effectively suppresses vibrations through a double-layer structure and support system, including vibration-proof gel pads and supporting legs, to isolate and attenuate external and internal vibrations.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If the imaging module is used to capture signals from nucleic acid molecules, then sequencing detection capability is achieved, but the system becomes highly sensitive to vibration causing image blur and reduced accuracy

Engineering Contradiction:
Improvesequencing detection capabilityVSAvoidvibration sensitivity
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The body is divided into an upper structure and a lower structure separated by an intermediate structure, creating a segmented dual-layer configuration. This segmentation isolates the imaging module (mounted on the upper structure) from vibrations generated by the lower structure, reducing vibration sensitivity while maintaining sequencing detection capability

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The intermediate structure acts as a mediator between the upper and lower structures. It transmits necessary mechanical support while filtering and attenuating vibration transmission, serving as an isolation layer that protects the imaging module from harmful vibrations generated by the lower structure

Inventive Principle:
Principle #24Intermediary (Mediator)

2Device complexity

If a single-layer body structure is used, then device complexity is reduced, but vibration damping effectiveness is insufficient

Engineering Contradiction:
Improvebody structure simplicityVSAvoidvibration damping effectiveness
Core Design Contradiction:
Device complexityVSReliability

Solution Approach 1:

The design transitions from a single-layer to a dual-layer body structure, adding a vertical dimension to vibration isolation. The upper and lower structures are separated by the intermediate structure, creating multiple vibration isolation pathways and enhancing damping effectiveness without excessive complexity

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

3Stability of the object's composition

If the natural frequency of the body is close to the internal excitation frequency, then resonance occurs amplifying vibration, but increasing the natural frequency requires structural modification

Engineering Contradiction:
Improvevibration suppressionVSAvoidstructural modification
Core Design Contradiction:
Stability of the object's compositionVSDevice complexity

Solution Approach 1:

The natural frequency of the body is adjusted to be greater than or equal to twice the internal excitation frequency, changing the frequency parameter to avoid resonance. This is achieved through the dual-layer structure design with the intermediate structure, which modifies the overall stiffness and mass distribution to achieve the desired frequency relationship

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The vibration damping structure significantly improves the imaging module's stability, ensuring clear image acquisition and accurate sequencing results by effectively reducing the impact of both external and internal vibrations.

Implementation Method 1

a natural frequency of the body is greater than or equal to times an internal excitation frequency

Methodology Applied
Scientific EffectVibration damping: Damping

Implementation Method 2

a natural frequency of the body is greater than or equal to times an internal excitation frequency

Methodology Applied
Scientific EffectResonance avoidance: Resonance

Implementation Method 3

support system, including vibration-proof gel pads and supporting legs, to isolate and attenuate external and internal vibrations

Methodology Applied
Scientific EffectVibration isolation: Damping

Data Source

PatentEP4036205B1Vibration dampening structure, detection system and sequencing system
Publication Date: 2026.01.07 GENEMIND BIOSCIENCES CO LTD
  • EP4036205B1 patent drawingFigure 1
  • EP4036205B1 patent drawingFigure 2
  • EP4036205B1 patent drawingFigure 3

AI summary

A vibration damping structure (60), a detection system and a sequencing system. The vibration damping structure (60) is used in the detection system. The vibration damping structure (60) comprises a main body (62) and a support body (64), the main body (62) is connected to the detection system by means of the support body (64), the main body (62) comprises an imaging module (10), an upper layer structure (66), a lower layer structure (68) and an intermediate structure (70), the imaging module (10) is mounted on the upper layer structure (66), the lower layer structure (68) bears the upper layer structure (66) by means of the intermediate structure (70), and the natural frequency of the main body (62) is greater than or equal to 2 times the internal excitation frequency.