Sequential Gas-Drug Injection Device for Reducing Injection Site Reactions

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Solution Overview

Problem

Current manual methods for administering drugs and gases through hypodermic injections are time-consuming, variable, and risk introducing contaminants, requiring trained healthcare professionals and increasing costs and discomfort for patients.

Innovation Solution

An automated injection device that sequentially delivers a drug and a gas to a patient using separate reservoirs and drive mechanisms, controlled by a controller to ensure precise and filtered administration without human intervention.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Object-affected harmful factors

If manual preparation of sandwich shots is performed by healthcare professionals, then gas can be introduced to reduce injection site reactions, but the process becomes time-consuming and requires trained professionals

Engineering Contradiction:
Improveinjection site reactionsVSAvoidinjection preparation time
Core Design Contradiction:
Object-affected harmful factorsVSLoss of time

Solution Approach 1:

The device pre-loads both the drug and gas into separate reservoirs before the injection procedure. The gas is drawn into the syringe barrel and positioned against the plunger in advance, so that when injection is needed, both components are ready for immediate sequential delivery without time-consuming manual preparation

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The device automatically performs the sequential injection of gas followed by drug without requiring manual intervention. The system self-regulates the injection process, eliminating the need for trained healthcare professionals to perform the time-consuming manual sandwich shot preparation while still providing the benefit of reduced injection site reactions

Inventive Principle:
Principle #25Self-service

2Object-affected harmful factors

If manual sandwich shot preparation is performed, then gas can be introduced to reduce pain and bruising, but inconsistency in volumes and ratios affects patient experience

Engineering Contradiction:
Improvepatient discomfortVSAvoiddosing consistency
Core Design Contradiction:
Object-affected harmful factorsVSManufacturing precision

Solution Approach 1:

The device incorporates sensors and control systems that monitor the injection process in real-time. The controller receives feedback from sensors detecting the presence and volume of gas and drug, automatically adjusting the injection parameters to ensure consistent dosing ratios and volumes, eliminating the variability inherent in manual preparation

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The invention replaces the manual mechanical process of preparing sandwich shots with an automated electromechanical system. The controller electronically manages the sequential injection of gas and drug with precise control over volumes and timing, substituting human manual操作 with an automated system that ensures dosing consistency while still reducing patient discomfort through gas introduction

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Object-affected harmful factors

If manual gas drawing is performed, then gas can be introduced to reduce injection reactions, but unfiltered air may introduce environmental contaminants

Engineering Contradiction:
Improveinjection site reactionsVSAvoidenvironmental contaminants
Core Design Contradiction:
Object-affected harmful factorsVSObject-generated harmful factors

Solution Approach 1:

The device introduces a filter as an intermediary component between the external environment and the injection system. The filter captures environmental contaminants from the air before it is drawn into the syringe reservoir, allowing the beneficial gas to be introduced for reducing injection site reactions while blocking harmful contaminants from entering the patient

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentUS20230085128A1Injection device for subcutaneous sequential delivery of gas and a drug
Publication Date: 2023.03.16 WEST PHARMACEUTICAL SERVICES INC
  • US20230085128A1 patent drawing
  • US20230085128A1 patent drawing
  • US20230085128A1 patent drawing

AI summary

A parenteral injection device comprises a housing defining an internal cavity and an output, a first reservoir disposed within the internal cavity, where the first reservoir defines a first chamber that is configured to store a drug and is in fluid communication with the output, a first drive mechanism to selectively force the drug from the first chamber, and a second reservoir disposed within the internal cavity, wherein the second reservoir defines a second chamber that is configured to store a gas and is in fluid communication with the output. The injection device further comprises a second drive mechanism to selectively force the gas from the second chamber, and a controller in signal communication with the first and second drive mechanisms, such that the controller is configured to selectively direct the first and second drive mechanisms to force the drug and gas from the first and second chambers, respectively, to the output in a predetermined sequence.