Serrated Nozzle for Complete Liquid Drop Transfer

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Solution Overview

Problem

Current microarray technologies face challenges in generating high-density hybridization sites on solid surfaces due to high manufacturing costs, mechanical deformation leading to inconsistent spot sizes, and issues with inkjet printing causing splashing and spreading of droplets, resulting in inconsistent hybridization data and potential cross-contamination.

Innovation Solution

A nozzle design with a serrated inner circumferential surface is used to facilitate the complete transfer of liquid droplets, reducing liquid-solid surface energy and adhesion, allowing for precise and efficient printing of biological materials without residual volume, enabling flexible and compact systems with reduced cleaning needs.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of manufacture

If mechanical micro spotting is used to print droplets, then the process is simple and inexpensive, but the pin tip deforms plastically after repeated use resulting in inconsistent spot size and shapes

Engineering Contradiction:
Improvesimplicity and low cost of microarray fabricationVSAvoidconsistency of spot size and shape
Core Design Contradiction:
Ease of manufactureVSManufacturing precision

Solution Approach 1:

The nozzle is segmented into multiple functional zones: a smooth entry section for droplet formation and a serrated exit section for controlled droplet release. This segmentation allows different parts of the nozzle to perform different functions optimally, preventing the uniform deformation problem of traditional pins while maintaining simplicity.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The nozzle features an asymmetric geometry with a smooth entry portion transitioning to a serrated exit portion. This asymmetric design creates controlled liquid-solid surface energy variations that prevent adhesion and ensure complete droplet transfer, eliminating the consistency problems associated with symmetric pin tips that deform uniformly.

Inventive Principle:
Principle #4Asymmetry

2Adaptability or versatility

If inkjet printing techniques are used to eject droplets, then the process is mature and widely used, but droplets splash or spread on the printing surface resulting in inconsistent hybridization data

Engineering Contradiction:
Improvematurity and widespread application of printing technologyVSAvoidconsistency of droplet placement and volume
Core Design Contradiction:
Adaptability or versatilityVSManufacturing precision

Solution Approach 1:

The serrated geometry at the nozzle exit creates a curved, controlled droplet release profile rather than a sharp ejection. This curved transition zone allows droplets to form smoothly and land gently on the substrate, preventing splashing and spreading while maintaining the maturity of inkjet technology.

Inventive Principle:
Principle #14Spheroidality (Curvature)

Solution Approach 2:

The nozzle applies local quality changes by having a smooth entry section for controlled droplet formation and a serrated exit section for controlled release. This localized geometric variation ensures consistent droplet characteristics without requiring changes to the overall inkjet system architecture.

Inventive Principle:
Principle #3Local quality

3Manufacturing precision

If soft printing is used to transfer droplets through liquid-solid contact, then consistent volumes of droplets can be generated, but a residual volume remains in the nozzle after printing which could cause cross-contamination

Engineering Contradiction:
Improveconsistency of droplet volumeVSAvoidresidual volume causing cross-contamination
Core Design Contradiction:
Manufacturing precisionVSObject-generated harmful factors

Solution Approach 1:

The serrated geometry, which initially might be expected to create more complex flow patterns, actually converts the harmful adhesion force into a beneficial effect. The serrations reduce liquid-solid surface energy and prevent droplet adhesion to the nozzle walls, ensuring complete droplet transfer and eliminating residual volume that would cause cross-contamination.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

4Device complexity

If traditional nozzles are used without surface modifications, then the device structure is simple, but liquid adhesion prevents complete droplet transfer

Engineering Contradiction:
Improvesimplicity of nozzle structureVSAvoidcompleteness of droplet transfer
Core Design Contradiction:
Device complexityVSManufacturing precision

Solution Approach 1:

The nozzle applies local quality changes by having a smooth entry section for controlled droplet formation and a serrated exit section for controlled release. This localized geometric variation ensures consistent droplet characteristics without requiring changes to the overall inkjet system architecture.

Inventive Principle:
Principle #3Local quality

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The serrated nozzle design ensures complete droplet transfer, improving printing efficiency and consistency, reducing cross-contamination, and enabling the printing of high-density arrays with precise control over droplet size and placement.

Implementation Method 1

The serrated inner circumferential surface reduces liquid-solid surface energy and adhesion, allowing for complete droplet transfer

Methodology Applied
Scientific EffectSurface energy reduction: Surface Tension

Implementation Method 2

The serrated inner circumferential surface reduces liquid-solid surface energy and adhesion, allowing for complete droplet transfer

Methodology Applied
Scientific EffectAdhesion reduction: Adhesive

Data Source

PatentUS7458661B2Method and apparatus for promoting the complete transfer of liquid drops from a nozzle
Publication Date: 2008.12.02 RGT UNIV OF CALIFORNIA
  • US7458661B2 patent drawing
  • US7458661B2 patent drawing
  • US7458661B2 patent drawing

AI summary

A printhead device for transferring liquid droplets from a nozzle includes a liquid source coupled to a nozzle via a microchannel. The nozzle is formed from an orifice having an inner circumferential surface, wherein at least a portion of the inner circumferential surface is serrated. Liquid droplets are transported from the source to the nozzle using a liquid droplet driver (e.g., employing a plurality of driving electrodes). Transfer of droplets to another surface can be accomplished by contacting a bulging droplet in the nozzle with a printing surface. The surface and/or nozzle are then moved relative to one another to effectuate complete transfer of the liquid drop from the nozzle.