Settable Surgical Implant Compositions for Moldable Tissue Repair
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Solution Overview
Problem
Existing surgical implants lack the ability to be moldable or formable at the implant site, making it difficult to optimize placement and fill voids in tissues, and often require catalysts for curing, which can be inconvenient and unpredictable.
Innovation Solution
Compositions are provided in the form of curable or settable parts that are mixed at the time of use, forming a moldable and flowable putty or paste that cures without a catalyst, with properties suitable for drilling or extrusion, and can be reheated to regain moldability if prematurely set.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Adaptability or versatility
If existing surgical implants are used, then they provide structural support, but they lack the ability to be moldable or formable at the implant site
Solution Approach 1:
The implant composition changes its physical parameters from a flowable state during delivery to a solidified state at the implant site, enabling moldability during placement while providing structural support after curing. This parameter transformation allows the material to be molded into desired shapes in situ.
Solution Approach 2:
The implant material exhibits dynamic properties, transitioning from a fluid-like state that allows molding and shaping to a rigid state that provides structural support. This dynamic behavior enables the implant to be adapted to various shapes and configurations at the implant site.
2Strength
If existing surgical implants are used, then they provide mechanical strength, but they require catalysts for curing which can be inconvenient and unpredictable
Solution Approach 1:
The implant composition contains all necessary curing components within its multi-component structure, eliminating the need for external catalysts. The components self-assemble and cure through mixing, simplifying the curing process while maintaining mechanical strength.
Solution Approach 2:
The implant is divided into multiple separate components that are mixed at the time of use. This segmentation allows each component to be optimized for specific functions while eliminating the need for external catalysts, as all necessary agents are contained within the component set.
3Adaptability or versatility
If the composition is made moldable for tissue repair, then it can be shaped at implant site, but it may lose mechanical strength during the moldable state
Solution Approach 1:
The implant composition undergoes a phase transition from a flowable or moldable state to a solidified state after implantation. During the moldable phase, the material can be shaped to fit the implant site, and after curing, it achieves the required mechanical strength for structural support.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The compositions offer a moldable and adhesive solution for tissue repair, providing mechanical strength and flexibility during application, with visual indicators of homogeneity and the ability to maintain moldability during curing, suitable for both hard and soft tissue repairs.
Implementation Method 1
compositions consisting of a set of two or more individual components, the components of a set comprising amounts of reagents which, upon mixing, react and cure into a final hardened form
Implementation Method 2
In one embodiment, the first component comprises water and the second component comprises a viscosity building agent
Data Source
AI summary
The present invention relates to settable compositions for use in surgery. The invention also provides related compositions, including surgical kits and packages, as well as methods of making and using the settable compositions.