Multi-Chamber Container With Shared Electrodes

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Solution Overview

Problem

Existing multi-well containers used in biochemical and pharmaceutical applications face inefficiencies due to either inability to address individual reaction spaces separately or having a large number of electrodes, leading to parasitic currents and reduced active and passive volumes.

Innovation Solution

A container design with a reduced number of electrodes, where n+x electrodes are provided for n reaction spaces, with electrodes arranged in rows or columns to maximize active volume, and contact elements are strategically placed to enhance electrical safety and minimize parasitic currents, allowing for individual addressing of reaction spaces.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If each reaction chamber is provided with two separate electrodes for individual addressing, then individual reaction spaces can be addressed separately, but the total number of electrodes increases significantly (2n electrodes for n reaction chambers)

Engineering Contradiction:
Improveindividual addressing capabilityVSAvoidnumber of electrodes
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

The patent merges the function of two separate electrodes into a single electrode structure. Each electrode serves as a common electrode for two adjacent reaction chambers, allowing individual addressing of each chamber while reducing the total electrode count from 2n to n+1 electrodes.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

Each electrode is designed to serve multiple functions simultaneously - it acts as one electrode for one reaction chamber and the corresponding electrode for the adjacent reaction chamber. This multi-functionality reduces the overall number of electrodes needed in the system.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Ease of operation

If a large number of electrodes are used to provide individual addressing, then all reaction chambers can be individually addressed, but parasitic currents increase and electrical safety decreases

Engineering Contradiction:
Improveindividual addressing capabilityVSAvoidparasitic currents
Core Design Contradiction:
Ease of operationVSObject-generated harmful factors

Solution Approach 1:

By merging electrode functions and reducing the total number of electrodes, the patent minimizes the number of electrical contacts and potential pathways for parasitic currents, thereby reducing harmful electrical effects while maintaining individual addressing capability.

Inventive Principle:
Principle #5Merging (Combining)

3Ease of operation

If more electrodes are installed in the container, then individual addressing is enabled, but the active and passive volumes of reaction chambers are reduced

Engineering Contradiction:
Improveindividual addressing capabilityVSAvoidactive volume of reaction chamber
Core Design Contradiction:
Ease of operationVSVolume of moving object

Solution Approach 1:

The patent merges electrode structures to reduce the number of electrode components within each reaction chamber. By making electrodes common to adjacent chambers, the volume occupied by electrodes in each individual chamber is reduced, thereby increasing the active volume available for reactions.

Inventive Principle:
Principle #5Merging (Combining)

4Ease of operation

If a large number of electrodes are used, then individual addressing is achieved, but material costs and equipment complexity increase

Engineering Contradiction:
Improveindividual addressing capabilityVSAvoidmaterial cost
Core Design Contradiction:
Ease of operationVSLoss of substance

Solution Approach 1:

The patent combines electrode functions so that one electrode serves two reaction chambers. This merging reduces the total number of electrodes from 2n to n+1, directly reducing material consumption and manufacturing costs while maintaining the ability to individually address each reaction chamber.

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This design reduces the number of electrodes required, saving material and equipment costs, increasing electrical safety, and maximizing active and passive volumes, while enabling efficient and precise electrical contact for high-throughput applications.

Implementation Method 1

each of which has at least one pair of electrodes for applying an electrical voltage to generate an electric field within the reaction chamber

Methodology Applied
Scientific EffectElectric field generation: Electric Field

Data Source

PatentEP2208779B1Container with multiple reaction chambers and electrodes
Publication Date: 2017.04.05 LONZA COLOGNE AG
  • EP2208779B1 patent drawingFigure 1
  • EP2208779B1 patent drawingFigure 2
  • EP2208779B1 patent drawingFigure 3

AI summary

The container (1) comprises three reaction chambers (2), which have an electrode pair consisting of first and second electrodes (3, 4, 5) for applying an electric voltage to generate an electric field inside the reaction chambers, are geometrically arranged in a row and/or are electrically switched in a row. The container is detachably connected with a radio frequency identification transponder. The electrodes are provided with contact elements (7), which are electrically contactable for applying the electric voltage. One of the electrodes of the reaction chamber is a common electrode. The container (1) comprises three reaction chambers (2), which have an electrode pair consisting of first and second electrodes (3, 4, 5) for applying an electric voltage to generate an electric field inside the reaction chambers, are geometrically arranged in a row and/or are electrically switched in a row. The container is detachably connected with a radio frequency identification transponder. The electrodes are provided with contact elements (7), which are electrically contactable for applying the electric voltage. One of the electrodes of the reaction chamber is a common electrode to the another reaction chamber and n+x electrodes are provided, where n is the number of the reaction chambers with n>= 3 and x is the number of rows with x>= 1. The common electrode is partially arranged between the two adjacent reaction chambers and geometrically arranged in the row. The common electrode of the both reaction chambers is provided with the contact element. A contact surface of the contact elements to the electrodes has an area of 8 mm 2>, where the contact elements are present on or inside the electrodes. The contact elements are formed in a pin-like, needle-like or screw-like manner and/or have a circular cross-section, and are arranged on the upper side of the electrodes and/or upwardly protrude from the electrodes. The electrodes downwardly protrude over a base of the container and/or a wall region of the reaction chambers. The reaction chamber is limited by the wall region, in which the transponder is integrated. Two groups of coupled first electrodes are formed such that the first electrodes of the different reaction chambers are electrically coupled. Two groups of coupled second electrodes are formed such that the second electrodes of the different reaction chambers are electrically coupled. A different group of reaction chambers contains respective group of coupled electrodes and a common reaction chamber contains two groups of coupled electrodes. The first electrodes are connected with one another over diodes, where each reaction chamber is arranged to one diode. Independent claims are included for: (1) a lid for a container; and (2) a process for producing a container.