Shatavari Extract Skincare Composition for Estrogen Receptor Stimulation

Resolve Bottlenecks,
Find Innovative SolutionsGenerate Solutions

Solution Overview

Problem

Existing skincare compositions containing Shatavari extract face challenges in determining optimal concentrations for binding to epidermal estrogen receptors, inhibiting 5α-reductase and tyrosinase, and maintaining stability, especially with high vitamin C levels which can cause irritation and solubility issues, limiting their effectiveness and formulation feasibility.

Innovation Solution

A skincare composition with specific amounts of Shatavari extract (0.01-2%) and reduced vitamin C (1-4%) levels, combined with hyaluronic acid, niacinamide, and other ingredients, is formulated to stimulate estrogen receptors, inhibit 5α-reductase and tyrosinase, and enhance skin firmness and brightness, using ethanol-based extraction methods to ensure stability and non-cytotoxicity.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If high vitamin C levels (10-15%) are used in skincare composition, then antioxidant activity and skin protection from light are improved, but skin irritation and solubility issues occur

Engineering Contradiction:

Improveantioxidant activityVSAvoidskin irritation

Core Design Contradiction:

ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent changes the concentration parameter of vitamin C from conventional high levels (10-15%) to optimized lower levels (1-4%), which resolves the contradiction by maintaining sufficient antioxidant activity while eliminating skin irritation and solubility issues associated with high concentrations

Inventive Principle:

Principle #35Parameter changes

Solution Approach 2:

The patent creates a composite formulation combining Shatavari extract with optimized vitamin C levels and other complementary ingredients (ferulic acid, vitamin E, niacinamide, hyaluronic acid), where the synergistic interaction of multiple components achieves effective antioxidant protection without the harmful effects of high single-ingredient concentrations

Inventive Principle:

Principle #40Composite materials

2Reliability

If high vitamin C levels (10-15%) are used in skincare composition, then collagen production is stimulated, but formulation stability and solubility deteriorate

Engineering Contradiction:

Improvecollagen productionVSAvoidformulation stability

Core Design Contradiction:

ReliabilityVSStability of the object's composition

Solution Approach 1:

The patent optimizes the vitamin C concentration parameter from conventional high levels to lower levels (1-4%), which maintains collagen production stimulation while improving formulation stability and solubility by reducing the risk of precipitation and interaction issues associated with high concentrations

Inventive Principle:

Principle #35Parameter changes

3Reliability

If Shatavari extract is used at conventional levels (0.0001-0.5%), then estrogenic activity is achieved, but manufacturing precision and cost-effectiveness deteriorate

Engineering Contradiction:

Improveestrogenic activityVSAvoidconcentration optimization

Core Design Contradiction:

ReliabilityVSManufacturing precision

Solution Approach 1:

The patent optimizes the Shatavari extract concentration parameter to a practical range (0.01-2%), which maintains effective estrogenic activity while improving manufacturing precision by eliminating the need for ultra-trace analysis and optimization, and enhancing cost-effectiveness by using measurable and economically viable concentrations

Inventive Principle:

Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition effectively stimulates estrogen receptors, inhibits 5α-reductase and tyrosinase, reduces skin aging, and improves skin firmness and brightness, while reducing production costs and avoiding irritation, with Shatavari extract demonstrating 767,358.626 times better estrogenic activity than standard β-estradiol and 40.22% 5α-reductase inhibition compared to finasteride.

Implementation Method 1

Shatavari extract has been used to bind to the epidermal estrogen receptor, inhibit tyrosinase, and/or inhibit 5α-reductase

Methodology Applied

Scientific EffectEstrogen receptor binding:

Implementation Method 2

inhibiting 5α-reductase and tyrosinase

Methodology Applied

Scientific EffectEnzyme inhibition:

Implementation Method 3

promote collagen production

Methodology Applied

Scientific EffectCollagen production stimulation:

Implementation Method 4

Natural vitamin C, in the form of L-ascorbic acid, has high antioxidant activity

Methodology Applied

Scientific EffectAntioxidant activity:

Implementation Method 5

prevent and treat skin aging caused by light

Methodology Applied

Scientific EffectFree radical scavenging:

Implementation Method 6

The efficiency of vitamin C is 4 times higher when used in combination with vitamin E

Methodology Applied

Scientific EffectSynergistic interaction:

Data Source

PatentUS20240398694A1Skincare composition containing shatavari extract

Publication Date: 2024.12.05 BANGKOK LAB & COSMETIC PUBLIC CO LTD

AI summary

The skincare composition contains Shatavari extract according to this invention. The composition comprises a particular amount of Shatavari extract that is effective in stimulating estrogen receptor, inhibiting 5α-reductase, inhibiting tyrosinase, and is non-cytotoxic. The said composition contains only essential ingredients that do not interfere with the absorption of active ingredients and cause no irritation. In one embodiment, the skincare gel comprises edetate disodium, high molecular weight hyaluronic acid, medium molecular weight hyaluronic acid, low molecular weight hyaluronic acid, niacinamide, Shatavari extract, 2-phenoxyethanol, carbomer, lactic acid, and water.