Sheath Flow Impedance Particle Analyzer Parallel Processing
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Solution Overview
Problem
Existing sheath flow impedance particle analyzers have a long measurement cycle and slow measurement speed due to sequential processing steps.
Innovation Solution
Incorporating a first auxiliary negative pressure source and a buffering cell to enable parallel processing of sample preparation and waste fluid discharge, reducing the time required for each measurement cycle by allowing simultaneous actions such as cleaning, sample loading, and fluid discharge.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If sequential processing steps are used for sample preparation and measurement, then the measurement process is simple and reliable, but the measurement cycle is long and measurement speed is slow
Solution Approach 1:
The patent divides the measurement system into multiple independent modules: pre-mixing cell, sheath flow impedance counting cell, front sheath fluid cell, rear sheath fluid cell, and waste fluid cell. Each module can operate independently, allowing sample preparation and waste discharge to proceed simultaneously during measurement cycles.
Solution Approach 2:
The patent implements preliminary actions by preparing samples in the pre-mixing cell and loading them into the sheath flow impedance counting cell before the actual measurement begins. The system pre-charges reagents and samples in advance, so that when measurement starts, the sample is already ready for immediate analysis.
Solution Approach 3:
The patent ensures continuous operation by overlapping multiple processes: while the sheath flow impedance counting cell is measuring samples, the pre-mixing cell is simultaneously preparing new samples and the waste fluid cell is discharging waste. This continuous pipeline eliminates idle time and maintains constant productive action throughout the measurement cycle.
2Loss of time
If multiple processing steps are performed simultaneously, then the measurement cycle is shortened and measurement speed is increased, but the system complexity increases
Solution Approach 1:
The patent merges multiple functions into integrated cells: the pre-mixing cell combines sample loading, reagent mixing, and preparation functions; the sheath flow impedance counting cell integrates sample introduction, sheath fluid formation, and measurement functions; the waste fluid cell handles both waste collection and discharge functions. This consolidation reduces the number of separate components needed.
Solution Approach 2:
The sheath flow impedance counting cell serves multiple purposes: it acts as the measurement chamber, the sample introduction vessel, the sheath fluid delivery system, and the waste discharge point. The front and rear sheath fluid cells similarly provide both fluid storage and flow control functions, reducing the need for dedicated separate components.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The solution significantly shortens the measurement cycle and increases measurement speed by allowing multiple steps to be performed concurrently, thereby improving the efficiency of the particle analysis process.
Implementation Method 1
a first auxiliary negative pressure source, the first auxiliary negative pressure source comprises at least one low pressure port and a first connecting port, the low pressure port is connected to the sample needle or the rear sheath waste fluid cell, and the first auxiliary negative pressure source is connected to the waste fluid cell by the first connecting port
Data Source
AI summary
A sheath flow impedance particle analyzer includes a pre-mixing cell, a sample needle, a sheath flow impedance counting cell, a front sheath fluid cell, a rear sheath fluid cell, a rear sheath waste fluid cell, a waste fluid cell, and a first auxiliary negative pressure source. The first auxiliary negative pressure source includes at least one low pressure port, and a valve for controlling the low pressure port to open or close, the low pressure port being connected to the sample needle or the rear sheath waste fluid cell. During measurement of a sample by the sheath flow impedance counting cell, at least the negative pressure of the first auxiliary negative pressure source enables the sample needle to transfer a sample liquid or enable the rear sheath waste fluid cell to discharge a waste fluid.