Low-Amplitude Signal Detection via Shielded Transduction

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Solution Overview

Problem

Current methods in chemistry and biochemistry require the actual presence of chemical or biochemical effector agents to interact with target systems, but it is unclear whether the effector's presence is necessary for its function, leading to questions about simulating effector functions using energetic modes characteristic of the effector molecules.

Innovation Solution

A method and apparatus to produce and transduce low-frequency time-domain signals characteristic of effector molecules, which are then used to mimic the effects of these molecules on target systems by exposing them to these signals, without the need for the actual effector agent, using a shielded environment, noise injection, and signal processing techniques.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If chemical or biochemical effector agents are used to interact with target systems, then the desired biological or chemical effect is achieved, but the complexity of the system increases and requires handling of actual effector molecules

Engineering Contradiction:
Improveeffector functionVSAvoidsystem complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent creates electromagnetic signal copies of effector molecules by recording their characteristic low-frequency signals in a shielded environment. These signal copies can then be used to produce effector-like effects on target systems without requiring the actual effector molecules, thereby reducing system complexity while maintaining functional reliability

Inventive Principle:
Principle #26Copying

Solution Approach 2:

The patent replaces the mechanical/chemical approach of delivering actual effector molecules with an electromagnetic field-based approach. By transducing effector molecules into characteristic electromagnetic signals and using these signals to affect target systems, the system eliminates the need for physical handling and delivery of chemical substances

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Reliability

If actual effector agents are present in the target environment, then effector functions are achieved, but the cost and availability constraints increase

Engineering Contradiction:
Improveeffector functionVSAvoideffector agent availability
Core Design Contradiction:
ReliabilityVSQuantity of substance

Solution Approach 1:

The patent creates electromagnetic signal copies of effector molecules that can be reproduced and transmitted without depleting the original effector substance. This signal copying approach eliminates availability constraints since electromagnetic signals can be generated on-demand without requiring physical presence or delivery of the actual effector molecules

Inventive Principle:
Principle #26Copying

3Adaptability or versatility

If low-frequency time-domain signals are recorded from effector molecules, then the ability to simulate effector functions is enabled, but the measurement precision requirements increase due to very low signal amplitudes

Engineering Contradiction:
Improveeffector function simulationVSAvoidsignal detection precision
Core Design Contradiction:
Adaptability or versatilityVSMeasurement precision

Solution Approach 1:

The patent implements a highly specialized shielded recording environment with magnetic shielding, electromagnetic shielding, and controlled acoustic conditions. This localized optimization of the recording environment creates a quiet zone that enables detection of extremely low-amplitude signals (on the order of 10^-18 to 10^-20 Newtons) that would otherwise be indistinguishable from environmental noise

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The patent uses a transducer as an intermediary device that converts mechanical vibrations from effector molecules into electrical signals that can be recorded and processed. This transduction step enables the measurement of extremely weak mechanical signals by converting them into a more measurable electrical domain while maintaining the characteristic signal information

Inventive Principle:
Principle #24Intermediary (Mediator)

4Measurement precision

If shielded environments and noise injection techniques are used to detect low-amplitude signals, then the ability to capture effector molecule signals is improved, but the device complexity increases

Engineering Contradiction:
Improvesignal detection precisionVSAvoiddetection system complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent implements a highly specialized shielded recording environment with magnetic shielding, electromagnetic shielding, and controlled acoustic conditions. This localized optimization of the recording environment creates a quiet zone that enables detection of extremely low-amplitude signals (on the order of 10^-18 to 10^-20 Newtons) that would otherwise be indistinguishable from environmental noise

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The patent employs periodic noise injection at specific frequency ranges (1-1000 Hz) to stimulate the effector molecules and enhance the detectability of their characteristic signals. By injecting noise periodically and analyzing the system's response at these specific frequencies, the method amplifies the effector signal above the background noise level, enabling detection without requiring overly complex continuous monitoring systems

Inventive Principle:
Principle #19Periodic action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach allows for achieving effector-specific results in systems responsive to the effector molecules by identifying optimized time-domain signals through noise injection and signal processing, enabling the simulation of effector functions and potential applications in drug delivery and nanofabrication.

Implementation Method 1

placing a sample containing the agent in a container having both magnetic and electromagnetic shielding

Methodology Applied
Scientific EffectElectromagnetic shielding: Faraday Cage

Implementation Method 2

placing a sample containing the agent in a container having both magnetic and electromagnetic shielding

Methodology Applied
Scientific EffectMagnetic shielding: Magnetic Field

Implementation Method 3

injecting noise into the recording apparatus at a level that enhances the ability to observe low-frequency stochastic events produced by the compound

Methodology Applied
Scientific EffectStochastic resonance:

Implementation Method 4

exposing the target system to electromagnetic waves produced by 'transducing' a time-domain signal of the effector compound

Methodology Applied
Scientific EffectElectromagnetic transduction: Electromagnetic Induction

Data Source

PatentUS9417257B2System and method for collecting, storing, processing, transmitting and presenting very low amplitude signals
Publication Date: 2016.08.16 NATIVIS INC
  • US9417257B2 patent drawing
  • US9417257B2 patent drawing
  • US9417257B2 patent drawing

AI summary

A method and apparatus for producing an effect of a chemical or biochemical agent on a system responsive to such agent, are disclosed. In practicing the method, a plurality of low-frequency time-domain signals of the agent are generated, each at a different at a different noise level within a selected noise level range. The signals are analyzed by producing spectral plots of the time-domain signals, and identifying an optimized agent-specific time-domain signal based on information in the spectral plots. A chemical or biological system responsive to the agent is exposed to the optimized time-domain signal by placing the system within the magnetic field of an electromagnetic transducer, and applying the signal to the transducer at a signal amplitude and for a period sufficient to produce in the system an agent-specific effect on the system.