Short-Pulse Spinal Cord Modulation for Paresthesia-Free Relief

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Conventional spinal cord stimulation (SCS) systems rely on long pulse width electrical pulses to generate tingling or paresthesia, which may not be comfortable for patients and require higher power consumption, while shortening pulse widths to avoid paresthesia poses challenges in achieving effective pain relief.

Innovation Solution

Implementing short pulse width waveforms (less than 50 microseconds) with frequencies ranging from 2 Hz to 1,500 Hz for spinal cord modulation, targeting specific neural populations to inhibit pain without inducing paresthesia, using simplified systems and procedures.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If long pulse width electrical pulses (greater than 50 microseconds) are used for spinal cord stimulation, then pain relief is achieved through paresthesia generation, but power consumption increases and patient comfort decreases

Engineering Contradiction:
Improvepain relief effectivenessVSAvoidpower consumption
Core Design Contradiction:
ReliabilityVSUse of energy by moving object

Solution Approach 1:

The patent changes the pulse width parameter from conventional long durations (greater than 50 microseconds) to short durations (less than 50 microseconds, specifically 10-30 microseconds). This parameter change allows achievement of pain relief through a different mechanism (direct neural inhibition rather than paresthesia), while simultaneously reducing power consumption since shorter pulses require less energy delivery.

Inventive Principle:
Principle #35Parameter changes

2Reliability

If long pulse width electrical pulses are used, then pain relief is achieved, but patient comfort deteriorates due to uncomfortable paresthesia sensations

Engineering Contradiction:
Improvepain relief effectivenessVSAvoidpatient discomfort from paresthesia
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

By changing the pulse width parameter to short durations (10-30 microseconds), the patent eliminates the generation of paresthesia sensations that cause patient discomfort. The short pulses directly inhibit pain transmission neurons without activating the sensory pathways that produce tingling sensations, thereby maintaining pain relief effectiveness while improving patient comfort.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent extracts or separates the pain relief function from the paresthesia generation function. Conventional SCS relies on paresthesia to mask pain, but this invention achieves pain relief through a different mechanism (direct neural inhibition) that does not require paresthesia, effectively removing the harmful side effect while preserving the therapeutic benefit.

Inventive Principle:
Principle #2Taking out (Extraction)

3Use of energy by moving object

If short pulse width waveforms (less than 50 microseconds) are used to avoid paresthesia, then power consumption is reduced, but achieving effective pain relief becomes challenging

Engineering Contradiction:
Improvepower consumptionVSAvoidpain relief effectiveness
Core Design Contradiction:
Use of energy by moving objectVSReliability

Solution Approach 1:

The patent successfully uses short pulse width (10-30 microseconds) parameters to reduce power consumption while maintaining pain relief effectiveness. The key is that the short pulses are delivered at appropriate amplitudes and frequencies to directly inhibit pain transmission neurons in the spinal cord, providing an alternative mechanism to conventional long-pulse SCS.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Achieves pain relief without paresthesia and reduced power consumption by modulating neural activity, selectively affecting smaller fibers and desensitizing neurons, thereby reducing chronic pain effectively.

Implementation Method 1

Implementing short pulse width waveforms (less than 50 microseconds) with frequencies ranging from 2 Hz to 1,500 Hz for spinal cord modulation, targeting specific neural populations to inhibit pain without inducing paresthesia

Methodology Applied
Scientific EffectElectrical stimulation: Electrical Impedance Tomography

Data Source

PatentUS12390645B1Spinal cord modulation for inhibiting pain via short pulse width waveforms, and associated systems and methods
Publication Date: 2025.08.19 NEVRO CORP
  • US12390645B1 patent drawing
  • US12390645B1 patent drawing
  • US12390645B1 patent drawing

AI summary

Short pulse width spinal cord modulation for inhibiting pain with reduced side effects and associated systems and methods are disclosed. In particular embodiments, modulation signal has pulse widths in the range of from about 10 microseconds to about 50 microseconds may be applied to the patient's spinal cord region to address chronic pain without using paresthesia or tingling to mask or cover the patient's sensation of pain. In other embodiments, modulation in accordance with similar parameters can be applied to other spinal or peripheral locations to address other indications.