Ventriculoperitoneal Shunt Pressure Responsive Element

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Solution Overview

Problem

Current ventriculoperitoneal shunts lack a non-invasive method to quickly and directly measure ventricular pressure, relying on invasive procedures or indirect imaging techniques, which pose risks and inefficiencies.

Innovation Solution

Incorporation of a pressure responsive element, such as a contrast container with microbubbles, operably coupled to the proximal catheter, which changes acoustic impedance in response to pressure changes, allowing for non-invasive measurement using ultrasound or sonic imaging.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If invasive procedures such as drilling a hole in the skull are used to take a ventricular pressure measurement, then ventricular pressure can be directly measured, but procedural risks and recovery time increase

Engineering Contradiction:
Improveventricular pressure measurementVSAvoidprocedural risks
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The patent introduces a contrast container with microbubbles as an intermediary element that can be non-invasively imaged via ultrasound. The microbubbles serve as a mediator between the ventricular pressure (which cannot be directly measured non-invasively) and the ultrasound imaging system, allowing indirect but accurate pressure assessment without invasive procedures

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent replaces the mechanical invasive measurement system (drilling, direct pressure sensors) with an acoustic field-based system. Ultrasound waves interact with the microbubbles in the contrast container to provide pressure information, substituting mechanical intrusion with non-invasive acoustic imaging

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Measurement precision

If invasive procedures are used to measure ventricular pressure, then direct measurement is achieved, but recovery time and risk of secondary infections increase

Engineering Contradiction:
Improveventricular pressure measurementVSAvoidrecovery time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent replaces invasive mechanical measurement with non-invasive ultrasound imaging of microbubbles. This substitution eliminates the need for surgical recovery while maintaining measurement capability, as the microbubbles can be imaged through intact tissue without requiring skull drilling or other invasive access

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Object-affected harmful factors

If CT scans or X-rays are used to indirectly measure ventricular pressure, then non-invasive measurement is achieved, but measurement precision and speed are reduced

Engineering Contradiction:
Improveinvasive proceduresVSAvoidventricular pressure measurement
Core Design Contradiction:
Object-affected harmful factorsVSMeasurement precision

Solution Approach 1:

The patent changes the physical parameter being measured from general anatomical changes (CT/X-ray density variations) to acoustic impedance changes of microbubbles. The microbubbles' strong acoustic contrast provides superior sensitivity to pressure changes compared to tissue density changes, enabling more precise and faster measurements

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent uses the acoustic 'contrast' (analogous to color in optical systems) of microbubbles to indicate pressure changes. The microbubbles provide a strong acoustic signal that changes with pressure, making them highly visible and measurable via ultrasound, similar to how a colored indicator changes with conditions in other measurement systems

Inventive Principle:
Principle #32Color changes

4Object-affected harmful factors

If CT scans or X-rays are used to measure ventricular pressure, then non-invasive measurement is achieved, but measurement speed is reduced due to requiring scans over several days

Engineering Contradiction:
Improveinvasive proceduresVSAvoidmeasurement time
Core Design Contradiction:
Object-affected harmful factorsVSLoss of time

Solution Approach 1:

The patent replaces slow, sequential multi-day imaging protocols with real-time ultrasound imaging of microbubbles. The acoustic imaging system provides immediate feedback on ventricular pressure through microbubble behavior, eliminating the time required for repeated CT or X-ray scans over several days

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Data Source

PatentUS9993631B2Ventriculoperitoneal shunt with pressure responsive element
Publication Date: 2018.06.12 JOHNS HOPKINS UNIVERSITY

AI summary

A ventriculoperitoneal shunt includes a proximal catheter, a distal catheter, a shunt valve operably coupling the proximal catheter to the distal catheter, and a contrast container containing contrast material configured to change acoustic impedance proportionally to a change in pressure applied to the contrast container.