Silica Fiber Topical Composition for Skin Tissue Repair
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Solution Overview
Problem
Current topical compositions for skin care lack effective methods to improve skin integrity, heal damaged skin, and reduce signs of aging, as they fail to provide sufficient flexibility and texture for collagen deposition and tissue repair.
Innovation Solution
Development of a topical composition comprising silica fiber powder or dust, created through electrospinning a sol-gel into a lightweight fiber mat, which is then processed into fine fragments and incorporated with a topical carrier, allowing for deposition in skin breaks to act as a collagen mimetic and promote cell infiltration and collagen deposition.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of manufacture
If conventional topical compositions are used for skin care, then they are easy to manufacture and apply, but they fail to provide sufficient flexibility and texture for collagen deposition and tissue repair
Solution Approach 1:
The patent combines silica fibers with topical carrier materials to create a composite composition that provides both the flexibility and texture needed for collagen deposition while maintaining ease of manufacture. The silica fibers act as a scaffold that mimics collagen structure, enabling the composition to serve multiple functions including tissue repair and skin regeneration.
2Ease of manufacture
If topical compositions lack effective methods for skin integrity improvement, then manufacturing and application remain simple, but skin healing and tissue repair are insufficient
Solution Approach 1:
The patent changes the physical and chemical parameters of the topical composition by incorporating silica fibers with specific dimensions and surface properties. These parameter changes enable the composition to effectively promote collagen deposition and skin healing while maintaining a relatively simple formulation that is easy to manufacture.
3Reliability
If silica fibers are incorporated into topical compositions, then skin healing and collagen deposition are improved, but the composition complexity increases
Solution Approach 1:
The patent segments the functional components of the topical composition by using discrete silica fibers as a separate phase within the topical carrier. This segmentation allows the silica fibers to provide specific structural and biological functions for skin healing while the carrier provides the vehicle for application, thereby managing composition complexity through functional separation.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The silica fiber composition enhances skin healing, reduces scarring, pain, and inflammation, providing a non-biodegradable scaffold for tissue regeneration and improving skin integrity, with improved flexibility and texture suitable for collagen deposition.
Implementation Method 1
The fiber composition is prepared by electrospinning a sol-gel into a silica fiber composition
Implementation Method 2
the composition may be prepared by electrospinning a sol-gel, which may be prepared with a silicon alkoxide reagent
Implementation Method 3
the sol-gel is produced via ripening of sol under controlled environmental conditions
Data Source
AI summary
Embodiments of the invention include topical compositions comprising silica fiber powder or dust and a topical carrier, for treatment of skin tissue. The silica fiber powder or dust may be generated from silica fiber mats that may be formed via electrospinning of a sol gel produced with a silicon alkoxide reagent, such as tetraethyl ortho silicate, alcohol solvent, and an acid catalyst.