Silicone Coating Agent for Medical Needles

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Solution Overview

Problem

Existing injection needles coated with silicone-based coatings still cause pain due to friction issues and coating durability problems, especially during multiple punctures.

Innovation Solution

A coating agent comprising polyorganosiloxanes with different polymerization degrees and amino or hydroxy group-containing polyorganosiloxanes, which form a strong film with improved lubricity and adhesiveness to reduce friction and prevent coating separation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If a silicone coating agent is applied to an injection needle surface, then friction at puncture is reduced and pain is relieved, but the coating film separates during multiple punctures causing increased friction

Engineering Contradiction:
Improvepiercing propertiesVSAvoidcoating durability
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The patent uses a composite coating system consisting of a base coat layer and a top coat layer with different functional compositions. The base coat provides strong adhesion to the needle surface, while the top coat provides lubricity. This layered composite structure resolves the contradiction by assigning different functions to different layers, preventing coating separation while maintaining low friction during multiple punctures

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The patent modifies the chemical composition parameters of the coating agent by incorporating specific components such as amino group-containing polyorganosiloxane and controlling the molecular weight distribution of polydiorganosiloxane. These parameter changes enhance both the adhesion strength and lubricity of the coating, allowing it to withstand multiple punctures without separation while maintaining low friction

Inventive Principle:
Principle #35Parameter changes

2Object-affected harmful factors

If a silicone coating agent is used to reduce friction, then pain at injection is relieved, but the coating separation increases friction during repeated use

Engineering Contradiction:
Improvepain at injectionVSAvoidcoating longevity
Core Design Contradiction:
Object-affected harmful factorsVSDuration of action of moving object

Solution Approach 1:

The patent applies a base coat layer first that creates a strong adhesive foundation on the needle surface before applying the top coat layer. This preliminary action of creating a robust base layer prevents subsequent coating separation during repeated punctures, ensuring the lubricity-enhancing top coat remains intact throughout multiple uses, thereby maintaining pain relief over time

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent designs a coating system where the top coat layer continuously provides lubricity throughout multiple punctures by preventing separation. The interconnected structure and strong adhesion of the layered coating ensure uninterrupted lubrication action, maintaining low friction and pain relief consistently across repeated injections rather than degrading over time

Inventive Principle:
Principle #20Continuity of useful action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The coating agent significantly reduces friction and enhances durability, providing effective pain relief and maintaining lubricity over multiple uses, thereby improving the piercing properties and longevity of medical instruments like needles.

Implementation Method 1

silicone is mainly used as a coating agent on an injection needle surface. Such silicone coating agents impart lubricity to an injection needle to reduce friction at puncture

Methodology Applied
Scientific EffectLubrication: Lubrication

Implementation Method 2

a coating agent that contains: (1) a polyorganosiloxane (1)... (3) an amino group-containing polyorganosiloxane or a hydroxy group-containing polyorganosiloxane

Methodology Applied
Scientific EffectAdhesion: Adhesive

Data Source

PatentEP3564330B1Coating agent and medical instrument surface-treated with said coating agent
Publication Date: 2023.12.27 TERUMO KK
  • EP3564330B1 patent drawingFigure 1A~1B
  • EP3564330B1 patent drawingFigure 2A~2B
  • EP3564330B1 patent drawing

AI summary

The coating agent of the present invention contains a polyorganosiloxane (1) represented by the following general formula (1), a polydiorganosiloxane (2) represented by the following general formula (2), and either one of an amino group-containing polyorganosiloxane (3) represented by the following general formula (3) and a hydroxy group-containing polyorganosiloxane (4) represented by the following general formula (4). According to the present invention, a coating agent having improved piecing properties and a medical instrument (in particular, needle) surface-treated (coated) with the coating agent are provided.