Silicone Skin Closure Composition for Flexible Joint Wound Sealing
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Solution Overview
Problem
Existing elastomeric topical skin adhesives struggle to provide effective closure and sealing for moving body joints like knees, wrists, and elbows, often compromising closure quality due to aggressive joint motion and the risk of post-surgical infections.
Innovation Solution
A novel silicone-based adhesive composition using vinyl terminated polydimethylsiloxane, polydimethylhydro-co-polydimethylsiloxane cross linker, surface treated silica particles, and a platinum catalyst, enabling rapid bonding through condensation and vinyl silylation reactions, allowing the adhesive to stretch and recover, and be applied without organic solvents.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Strength
If traditional cyanoacrylate-based TSA products are used, then strong bonding is achieved, but the adhesive cannot stretch and recover for moving joints
Solution Approach 1:
The patent changes the chemical composition parameters by using vinyl-terminated polydimethylsiloxane and polydimethylhydrosiloxane crosslinker instead of cyanoacrylate, enabling the adhesive to achieve both strong bonding and elastic stretchability up to 160% for moving joints
Solution Approach 2:
The patent creates a composite silicone-based adhesive system combining multiple components (vinyl-terminated polydimethylsiloxane, polydimethylhydrosiloxane crosslinker, platinum catalyst) to achieve properties that neither component alone could provide, specifically both strength and elasticity
2Adaptability or versatility
If silicone-based adhesives are used for moving joints, then elasticity is improved, but closure quality may be compromised by aggressive motion
Solution Approach 1:
The patent makes the adhesive dynamic by enabling it to stretch with joint motion and then fully recover to its original dimensions, allowing the closure to adapt to aggressive motion while maintaining sealing integrity
Solution Approach 2:
The patent optimizes the crosslinking density and silicone polymer structure to achieve the right balance between elasticity for motion and sufficient bonding strength to maintain watertight closure during aggressive joint movement
3Productivity
If rapid curing is achieved through conventional catalysts, then bonding speed is improved, but skin reactions may occur
Solution Approach 1:
The patent uses a platinum catalyst system that enables rapid curing at body temperature without requiring harsh chemicals or extended drying times, reducing skin exposure to harmful substances while achieving fast bonding
Solution Approach 2:
The silicone-based adhesive system creates an inert, biocompatible environment on the skin that reduces allergic reactions and irritation while maintaining rapid curing performance through the platinum-catalyzed crosslinking mechanism
4Object-affected harmful factors
If the adhesive is applied without organic solvents, then safety is improved, but drying time may be extended
Solution Approach 1:
The patent replaces the evaporation-based drying mechanism (which requires organic solvents) with a chemical crosslinking mechanism catalyzed by platinum, allowing the adhesive to cure rapidly at body temperature without organic solvents and without extended drying time
Solution Approach 2:
The patent changes the curing mechanism from solvent-evaporation-based to crosslinking-based, enabling the adhesive to achieve rapid bonding without organic solvents by optimizing the crosslinker and catalyst system for body temperature operation
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The adhesive achieves strong, flexible, and elastic bonding comparable to cyanoacrylate-based products, with improved durability and reduced skin reactions, suitable for wound closure systems on movable joints.
Implementation Method 1
The bonding formation is enabled by the condensation reaction between the silanol functions on the surface of silica particle and the OH functions on the skin.
Implementation Method 2
The platinum based novel catalyst also activates vinyl silylation reaction to allow vinyl terminated silicone polymer to cross link simultaneously to the condensation reaction.
Implementation Method 3
the invented silicone-based TSA when combined with traditional wound closure devices can be stretched to 160% of its original length and fully recover to its original dimension.
Data Source
AI summary
Novel compositions and systems for closure of wounds are disclosed. The compositions provide devices of improved flexibility and elasticity and are readily applied to wound sites or over wound closure devices. The present invention is also directed to a novel platinum catalyst for use in such compositions. The catalyst provides for rapid curing on topical surfaces such as skin and bonds to such surfaces in about 2-5 minutes.