Silicone Pressure-Sensitive Adhesive Tapes for Optical PCR Analysis

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Solution Overview

Problem

Existing test sample cards for liquid samples in light-based analytical methods are affected by refractive index differences between the liquid and air, leading to contamination risks and inefficiencies in PCR techniques due to adhesive agents.

Innovation Solution

Silicone adhesive tapes with high optical clarity, high light transmission, and low haze are developed, featuring a flexible substrate with a silicone pressure-sensitive adhesive, which minimizes interference and contamination, suitable for medical and microbiology applications.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Strength

If conventional adhesives are used in test sample cards, then the adhesive provides bonding strength, but the adhesive agents cause contamination risks and interfere with PCR techniques

Engineering Contradiction:

Improvebonding strengthVSAvoidcontamination risk

Core Design Contradiction:

StrengthVSObject-affected harmful factors

Solution Approach 1:

The patent changes the chemical composition parameters of the adhesive by using silicone-based materials with specific molecular structures (polydimethylsiloxane backbone) that inherently lack the contaminating agents found in conventional adhesives, thereby maintaining bonding strength while eliminating contamination risks for PCR applications

Inventive Principle:

Principle #35Parameter changes

Solution Approach 2:

The silicone adhesive creates an inert chemical environment that does not react with or contaminate biological samples, allowing PCR techniques to proceed without interference from adhesive agents, thus protecting the sample integrity

Inventive Principle:

Principle #39Inert atmosphere (Inert environment)

2Strength

If conventional adhesives are used in test sample cards, then the adhesive provides bonding strength, but the refractive index differences between liquid sample and air detrimentally impact light-based analytical methods

Engineering Contradiction:

Improvebonding strengthVSAvoidlight-based analytical evaluation accuracy

Core Design Contradiction:

StrengthVSMeasurement precision

Solution Approach 1:

The patent introduces a silicone adhesive layer as an intermediary medium between the liquid sample and air that has refractive index properties minimizing the refractive index mismatch, thereby reducing optical distortions and improving the accuracy of light-based analytical evaluations while maintaining adequate bonding strength

Inventive Principle:

Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent modifies the optical parameters of the adhesive interface by selecting silicone materials with refractive indices that bridge the gap between liquid samples and air, reducing refraction effects and enhancing light transmission for more accurate analytical measurements

Inventive Principle:

Principle #35Parameter changes

3Illumination intensity

If high light transmission is achieved in the adhesive tape, then the optical clarity is improved, but the adhesive bonding strength may be compromised

Engineering Contradiction:

Improvelight transmissionVSAvoidadhesive bonding strength

Core Design Contradiction:

Illumination intensityVSStrength

Solution Approach 1:

The patent employs composite material design by combining silicone polymers with specific molecular structures that simultaneously provide high light transmission properties and adequate adhesive bonding strength, achieving a balance between optical clarity and mechanical performance through the synergistic properties of the silicone-based composition

Inventive Principle:

Principle #40Composite materials

Data Source

PatentUS20250326954A1Silicone Based Pressure Sensitive Adhesive Tapes

Publication Date: 2025.10.23 AVERY DENNISON CORP

AI summary

Silicone pressure sensitive adhesives are described which exhibit unique properties enabling their use in various medical, microbiology, and life science applications. Also described are various silicone adhesive tape constructions which include one or more regions of the silicone-based pressure sensitive adhesives. In addition, systems and methods of using the silicone adhesives and silicone adhesive tapes are described, such as evaluating biological samples using the silicone adhesive tapes.