Silicone Skin Closure Composition for Flexible Watertight Joints
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Solution Overview
Problem
There is a need for elastomeric topical skin adhesives that can effectively close moving body joints like knees, wrists, and elbows while providing watertight closure to prevent post-surgical infections, and incorporating antimicrobial agents to prevent microbial contamination.
Innovation Solution
A novel silicone-based adhesive composition using a platinum catalyst and vinyl terminated polydimethylsiloxane, polydimethylhydro-co-polydimethylsiloxane cross linker, surface treated silica particles, and an antimicrobial agent like triclosan, which allows for rapid bonding and elasticity, enabling stretchability up to 160% of original length with full recovery, and antimicrobial properties.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Strength
If traditional cyanoacrylate-based TSA products are used, then strong skin holding forces are achieved, but the adhesive cannot be stretched and lacks elasticity
Solution Approach 1:
The patent changes the chemical composition parameters by using vinyl terminated polydimethylsiloxane and polydimethylhydro-co-polydimethylsiloxane cross linker instead of traditional cyanoacrylate, enabling the adhesive to achieve both strong skin holding forces and high elasticity with 160% stretchability
Solution Approach 2:
The invention creates a composite silicone-based adhesive system combining multiple silicone polymers, cross linkers, and catalysts to achieve a material that simultaneously provides strong adhesion and exceptional elasticity, unlike traditional single-component cyanoacrylate adhesives
2Adaptability or versatility
If silicone-based adhesive is used for moving joints, then elasticity and stretchability are improved, but watertight closure and infection prevention are compromised
Solution Approach 1:
The patent merges multiple functions into a single adhesive system: elasticity for joint movement, watertight sealing, and antimicrobial protection through integrated triclosan, achieving comprehensive wound protection without requiring separate products
Solution Approach 2:
The invention develops a composite material system combining silicone polymers for elasticity, cross-linking agents for sealing, and triclosan for antimicrobial protection, creating a multi-functional adhesive that simultaneously addresses all three requirements
3Reliability
If antimicrobial agents are added to TSA, then infection prevention is improved, but the complexity of the composition increases
Solution Approach 1:
The adhesive system provides self-service by integrating triclosan directly into the TSA formulation, allowing the product to simultaneously perform adhesion and antimicrobial functions without requiring separate application steps or additional devices
Solution Approach 2:
The patent creates a universal wound closure product that combines adhesive, elastic, sealing, and antimicrobial properties in a single composition, eliminating the need for multiple separate products and simplifying the overall treatment protocol
4Productivity
If rapid curing is achieved at body temperature, then application speed is improved, but the bonding reaction may be insufficient at ambient temperature
Solution Approach 1:
The patent optimizes reaction parameters by selecting catalysts and chemical compositions that enable rapid curing at body temperature while maintaining adequate bonding strength at ambient temperature through controlled reaction kinetics
Solution Approach 2:
The adhesive exhibits different reaction rates under different conditions: slower initial bonding at ambient temperature for adequate strength development, and accelerated curing at body temperature for rapid final set, creating a periodic action that adapts to environmental conditions
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The adhesive composition provides strong skin holding forces, rapid curing at body temperature, and effective antimicrobial protection, maintaining elasticity and preventing wound infections, especially suitable for joints.
Implementation Method 1
The bonding formation is enabled by the condensation reaction between the silanol functions on the surface of silica particle and the OH functions on the skin
Implementation Method 2
The platinum based novel catalyst also activates vinyl silylation reaction to allow vinyl terminated silicone polymer to cross link simultaneously to the condensation reaction
Implementation Method 3
the invented silicone-based TSA when combined with traditional wound closure devices can be stretched 160% of its original length and fully recover to its original unstretched dimension
Implementation Method 4
Because there is a potential for microbial contamination and infection of the wound, there is also a further need in providing antimicrobial agents as a part of any novel TSA
Data Source
AI summary
Novel compositions and systems for closure of wounds with antimicrobial effectiveness provide devices of improved flexibility and elasticity and are readily applied to wound sites or over wound closure devices. A novel platinum catalyst comprising platinum tetramethyldivinyl disiloxane diethyl maleate complex for use in such compositions provides for rapid curing on topical surfaces such as skin and bonds to such surfaces in about 2-5 minutes.