Siloxane Molecular Membrane Uniformity via Para-Aminophenyl Silane
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Solution Overview
Problem
The formation of siloxane-based molecular membranes using organic silane molecules like APTES often results in agglomeration, leading to variations in the amount of molecules per unit area, which decreases the detection precision of multi-array biochips.
Innovation Solution
A siloxane-based molecular membrane is formed using organic compounds represented by specific formulas, such as p-aminophenyltrimethoxysilane, with hydrolysis and dehydration condensation reactions at temperatures of 50°C or lower, preventing agglomeration and ensuring consistent molecule distribution.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Manufacturing precision
If organic silane molecules like APTES are used to form siloxane-based molecular membranes, then the membrane can be formed on the base material surface, but agglomeration occurs leading to variations in molecule distribution
Solution Approach 1:
The patent changes the chemical parameters of the silane molecule by introducing specific substituent groups (electron-withdrawing groups at para positions and electron-donating groups at ortho positions) to modify the reactivity and steric effects, thereby preventing agglomeration and achieving uniform molecule distribution in the siloxane-based molecular membrane
Solution Approach 2:
The patent creates a composite molecular structure combining silane backbone with specific aromatic substituents (aminophenyl groups with additional functional groups), forming a new type of silane compound that prevents agglomeration while maintaining membrane formation capability
2Measurement precision
If conventional silane molecules are used, then membrane formation is achieved, but detection precision decreases due to agglomeration
Solution Approach 1:
By modifying the chemical parameters of the silane molecule through specific substituent groups, the patent achieves uniform molecule distribution which directly improves detection precision by eliminating variations in molecule density across the membrane surface
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach prevents agglomeration in the siloxane-based molecular membrane, maintaining consistent molecule distribution and enhancing the detection precision of multi-array biochips and sensors.
Implementation Method 1
a siloxane based molecular membrane formed on the base material by use of an organic compound
Implementation Method 2
hydrolysis and dehydration condensation reactions at temperatures of 50°C or lower
Data Source
AI summary
A structure body includes a base material and a siloxane based molecular membrane formed on the base material by use of an organic compound represented by Formula (1) or Formula (2):wherein any one of R1 to R5 is an amino group, others of R1 to R5 are each independently hydrogen or an alkyl group, R7 to R9 are each independently any one of hydroxy group, alkoxy group, alkyl group, and phenyl group on condition that one or more of R7 to R9 are each independently a hydroxy group or an alkoxy group, and R6 is an alkyl group.