Single-Lumen Blood Pumping Device with Flexible Membrane

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Solution Overview

Problem

Existing blood pumping devices face challenges in manufacturing costs and blood clotting due to sharp edges and corners, leading to increased expenses and risks of clot formation.

Innovation Solution

A pressure actuated single-lumen blood pumping device with a flexible tubular membrane in a pressure transfer chamber, eliminating sharp edges and corners, and a blood transfer conduit with lumen branches that facilitate smooth blood flow and reduce residence time.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Strength

If a membrane pump with rigid housing and sharp edges is used, then the structural strength is improved, but the risk of blood clotting increases due to sharp edges and corners

Engineering Contradiction:
Improvestructural strengthVSAvoidblood clotting risk
Core Design Contradiction:
StrengthVSObject-affected harmful factors

Solution Approach 1:

The patent replaces the rigid housing with a flexible membrane that forms a blood chamber with entirely rounded surfaces. The membrane is inflated to create a spherical or ellipsoidal blood chamber geometry, eliminating all sharp edges and corners that would cause blood damage and clotting. This curvature principle maintains structural integrity through the flexibility and elasticity of the membrane material while ensuring biocompatible blood flow paths.

Inventive Principle:
Principle #14Spheroidality (Curvature)

Solution Approach 2:

The patent uses a flexible membrane as the blood chamber boundary instead of a rigid housing. The membrane can be inflated and deflated to create and collapse the blood chamber, providing both structural strength and smooth, clot-free surfaces. The flexible nature of the membrane allows it to conform to rounded geometries and eliminates the need for sharp structural features.

Inventive Principle:
Principle #30Flexible shells and thin films

2Object-affected harmful factors

If multiple coating processes are applied to smoothen transitions, then the blood clotting risk is reduced, but the manufacturing time and cost increase

Engineering Contradiction:
Improveblood clotting riskVSAvoidmanufacturing time
Core Design Contradiction:
Object-affected harmful factorsVSLoss of time

Solution Approach 1:

The patent eliminates the need for multiple coating processes by designing the blood chamber with inherently rounded geometry from the membrane inflation process itself. The spherical or ellipsoidal shape created by inflating the membrane provides smooth transitions throughout the blood chamber without requiring additional smoothening steps.

Inventive Principle:
Principle #14Spheroidality (Curvature)

Solution Approach 2:

The patent employs a disposable membrane pump where the entire membrane assembly is replaced after use. This eliminates the need for complex, time-consuming coating processes to ensure clot-free surfaces, as the disposable nature of the device allows for simple manufacturing without expensive surface treatment steps.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

3Device complexity

If a single-lumen catheter with sequential blood flow is used, then the device complexity is reduced, but the blood residence time in the blood compartment becomes long increasing clotting risk

Engineering Contradiction:
Improvedevice complexityVSAvoidblood residence time
Core Design Contradiction:
Device complexityVSDuration of action of moving object

Solution Approach 1:

The spherical or ellipsoidal geometry of the inflated membrane blood chamber creates natural flow circulation patterns that reduce stagnant zones. The curved surfaces and lack of sharp corners promote continuous blood movement through the chamber, reducing residence time and clotting risk while maintaining the simple single-lumen catheter configuration.

Inventive Principle:
Principle #14Spheroidality (Curvature)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The device is manufactured at lower costs with reduced risk of blood clotting, achieving efficient net circulation and minimizing blood residence time, making it suitable for use in circulatory assist systems.

Implementation Method 1

the pressure transfer port communicating with the pressure transfer chamber for alternatingly transferring overpressure and under pressure from the pressure source to the pressure transfer chamber

Methodology Applied
Scientific EffectPressure transfer: Pressure Gradient

Implementation Method 2

a flexible tubular membrane in the pressure transfer chamber, the flexible tubular membrane having opposite ends and bounding a blood chamber

Methodology Applied
Scientific EffectFlexible membrane deformation: Elasticity

Data Source

PatentUS9636442B2Pressure actuated single-lumen blood pumping device
Publication Date: 2017.05.02 PULSECATH BV
  • US9636442B2 patent drawing
  • US9636442B2 patent drawing
  • US9636442B2 patent drawing

AI summary

A pressure actuated single-lumen blood pumping device has a housing (4) having a wall (19) bounding a pressure transfer chamber (11; 411). The housing (4) bounds a pressure transfer port (9) for connection to a pressure source, the pressure transfer port (9) communicating with the pressure transfer chamber (11; 411) for alternatingly transferring over pressure and under pressure from the pressure source to the pressure transfer chamber (11; 411). A flexible tubular membrane (2; 102; 202; 302; 402) is arranged in the pressure transfer chamber (11; 411). A blood transfer conduit (3; 103; 203; 303; 403) passes through the wall (19) bounding the pressure transfer chamber (11; 411) and the blood transfer conduit (3; 103; 203; 303; 403) connects to opposite ends (5, 6; 105; 405, 406) of the flexible tubular membrane (2; 102; 202; 302; 402).