Single-Spring Auto-Injector for Complete Dose Delivery

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Solution Overview

Problem

Existing auto-injectors face challenges such as user discomfort due to injection force and hand shaking, risk of incomplete doses, and complexity in operation, particularly for elderly or dexterity-impaired individuals, and often require multiple springs for needle insertion, retraction, and dose delivery.

Innovation Solution

An auto-injector design utilizing a single compression spring for needle insertion, dose delivery, and retraction, with a simplified trigger mechanism and a delay box to ensure complete dose delivery and safe needle retraction, featuring a low part count and reduced manufacturing costs.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If multiple springs are used for needle insertion, retraction, and dose delivery, then the functions are reliable, but the device complexity and manufacturing cost increase

Engineering Contradiction:
Improvefunction reliabilityVSAvoidspring system complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent combines multiple spring functions (needle insertion, dose delivery, and retraction) into a single compression spring system. The spring is configured to perform these different functions sequentially during operation, eliminating the need for separate springs for each function and thereby reducing device complexity while maintaining reliability.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The single compression spring is designed to serve multiple purposes: it drives needle insertion, delivers the medicament dose, and retracts the needle after injection. This multi-functional design reduces the number of components needed while ensuring all critical functions are performed reliably.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Device complexity

If a single compression spring is used for all functions, then device complexity is reduced, but ensuring complete dose delivery and safe retraction becomes more difficult

Engineering Contradiction:
Improvespring system complexityVSAvoiddose delivery completeness
Core Design Contradiction:
Device complexityVSReliability

Solution Approach 1:

The patent segments the single compression spring's operation into distinct phases: compression phase for needle insertion, injection phase for dose delivery, and retraction phase for needle withdrawal. This temporal segmentation allows one spring to perform multiple functions reliably by controlling when each function is activated during the injection cycle.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The spring system is designed with dynamic characteristics that automatically transition between different operational modes. The spring's compression, expansion, and locking mechanisms dynamically adapt to ensure complete dose delivery and safe retraction without requiring complex control systems.

Inventive Principle:
Principle #15Dynamics

3Measurement precision

If injection force is increased to ensure complete dose delivery, then dosing accuracy improves, but user discomfort and hand shaking increase

Engineering Contradiction:
Improvedose delivery accuracyVSAvoiduser discomfort
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The patent replaces manual mechanical injection force with an automated compression spring mechanism. The spring provides controlled, consistent force throughout the injection cycle, eliminating the need for the user to exert high forces while reducing hand shaking and discomfort. The mechanical system automatically ensures complete dose delivery.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The design ensures reliable, complete dose delivery with reduced user discomfort and operational complexity, minimizing the risk of incomplete doses and needle injuries, while reducing material and manufacturing costs.

Implementation Method 1

spring means capable of, upon activation: pushing the needle from a covered position inside the housing into an advanced position

Methodology Applied
Scientific EffectElasticity: Elasticity

Implementation Method 2

retracting the syringe with the needle into the covered position after delivering the medicament

Methodology Applied
Scientific EffectElasticity: Elasticity

Data Source

PatentUS12527916B2Auto-injector
Publication Date: 2026.01.20 SANOFI AVENTIS DEUT GMBH
  • US12527916B2 patent drawing
  • US12527916B2 patent drawing
  • US12527916B2 patent drawing

AI summary

An auto-injector for administering a dose of a liquid medicament includes an elongate housing arranged to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament, the housing having a distal end and a proximal end with an orifice intended to be applied against an injection site. The syringe is slidably arranged with respect to the housing. A spring capable of, upon activation: pushing the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end (P), operating the syringe to supply the dose of medicament (M), and retracting the syringe with the needle into the covered position. After delivering the medicament, an activator arranged to lock the spring in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring for injection.