Sinus Ostia Neuromodulation for Chronic Sinusitis Relief

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Solution Overview

Problem

Current treatments for chronic sinusitis, including pharmacotherapy and surgical interventions, are either temporary or fail to adequately address the underlying cause, leading to suboptimal efficacy and significant side effects.

Innovation Solution

A treatment device delivering energy to target sites within the nasal cavity, such as sinus ostia and cavity walls, to therapeutically modulate neural structures associated with chronic sinusitis, specifically parasympathetic nerves, reducing hyperactive mucosal secretions and soft tissue engorgement.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If pharmacotherapy is used to treat chronic sinusitis, then sinus ventilation is improved, but long-term side effects and suboptimal efficacy occur

Engineering Contradiction:
ImproveefficacyVSAvoidside effects
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent replaces pharmacological therapy with a mechanical/physical intervention - radiofrequency energy delivery through an end effector. This substitutes chemical-based treatment with a physical energy-based treatment that directly modifies neural tissue to reduce hyperactive mucosal secretions and soft tissue engorgement, thereby avoiding long-term pharmaceutical side effects while maintaining therapeutic efficacy.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent applies controlled thermal energy (radiofrequency) to change the physiological state of neural tissue. By delivering specific energy parameters (temperature, power, duration) to targeted neural structures, the treatment modifies neural signaling to reduce autonomic dysfunction, achieving sustained symptom relief without the cumulative side effects of long-term medication.

Inventive Principle:
Principle #35Parameter changes

2Reliability

If surgical intervention is used to treat chronic sinusitis, then sinus opening is achieved, but risks and complications increase

Engineering Contradiction:
Improvesinus ventilationVSAvoidsurgical risks
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent replaces traditional surgical mechanical intervention with a minimally invasive energy-based approach. Instead of using surgical instruments to physically open sinuses, the system delivers radiofrequency energy through a small end effector to modulate neural tissue, achieving sinus ventilation improvement without the risks of bleeding, scarring, or damage to healthy tissue associated with conventional surgery.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent applies treatment locally to specific neural targets within the sinus cavity rather than performing broad surgical intervention. The end effector delivers energy precisely to neural structures controlling autonomic function, affecting only the localized pathological processes while preserving surrounding healthy tissue, thereby reducing surgical complications.

Inventive Principle:
Principle #3Local quality

3Loss of time

If current treatments are applied, then symptoms are temporarily relieved, but underlying causes are not addressed

Engineering Contradiction:
Improvesymptom relief durationVSAvoidunderlying cause treatment
Core Design Contradiction:
Loss of timeVSReliability

Solution Approach 1:

The patent performs preliminary identification and targeting of the underlying neural mechanisms before treatment delivery. The system identifies specific neural structures responsible for hyperactive mucosal secretions and soft tissue engorgement, then applies energy modulation to these targets, addressing the root cause rather than merely treating symptoms after they manifest.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent incorporates real-time monitoring and feedback mechanisms to ensure accurate delivery of energy to the intended neural targets. This feedback control allows the system to adjust treatment parameters based on tissue response, ensuring that the underlying neural dysfunction is effectively modified while avoiding damage to surrounding structures, thereby providing sustained relief from the root cause.

Inventive Principle:
Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Minimally invasive and localized energy application effectively treats chronic sinusitis by disrupting neural signals, addressing the underlying cause without the drawbacks of traditional therapies.

Implementation Method 1

The energy delivered to the target site(s) may be sufficient to therapeutically modulate or interrupt neural signals associated with parasympathetic nerves that control autonomic function of the sinuses

Methodology Applied
Scientific EffectElectromagnetic neuromodulation: Electromagnetic Induction

Implementation Method 2

The energy delivered to the target site(s) is sufficient to therapeutically treat tissues of interest associated with the sinuses, specifically neural tissue

Methodology Applied
Scientific EffectThermal energy delivery: Heating

Data Source

PatentUS12616514B2Systems and methods for treating chronic sinusitis
Publication Date: 2026.05.05 NEURENT MEDICAL LTD
  • US12616514B2 patent drawing
  • US12616514B2 patent drawing
  • US12616514B2 patent drawing

AI summary

The invention generally relates to systems and methods for targeting of specific tissue(s) of interest within a sino-nasal region of a patient, specifically sinus regions (i.e., ostia and sinus cavities), for the treatment of chronic sinusitis conditions.