Skin Care Composition With Penetration Enhancers for Multi-Target Repair

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Solution Overview

Problem

Existing skin care compositions fail to effectively address issues such as photoaging, fine lines, wrinkles, skin elasticity, skin firmness, acne, inflammation, and bacterial growth, while also being inefficient in whitening, anti-glycation, and moisturizing.

Innovation Solution

A skin care composition comprising a combination of active components like tetrahydrocurcumin, ergothioneine, and tetrahydropiperine, along with auxiliary components like laurocapram and sucrose laurate, which synergistically inhibit tyrosinase activity, reduce inflammatory factors, and inhibit AGEs, while enhancing penetration and moisturizing effects.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional skin care compositions are used, then basic skin care functions are provided, but they fail to effectively address photoaging, inflammation, and whitening needs

Engineering Contradiction:
Improveeffectiveness in addressing photoaging, inflammation, and whiteningVSAvoidefficiency in whitening, anti-glycation, and moisturizing
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The patent combines multiple active components with distinct functions (tetrahydrocurcumin for anti-inflammatory, ergothioneine for whitening, phloretin for anti-glycation, retinol for anti-aging) into a single composition, creating synergistic effects that simultaneously address multiple skin concerns that conventional single-function products cannot resolve

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The invention uses composite active ingredient systems where each component targets specific skin problems (photoaging, inflammation, whitening, glycation) and works synergistically with others, creating a multi-functional formulation that exceeds the performance of individual ingredients or conventional single-purpose products

Inventive Principle:
Principle #40Composite materials

2Reliability

If high concentrations of active ingredients are used to improve efficacy, then skin care effects are enhanced, but penetration efficiency and skin absorption may be compromised

Engineering Contradiction:
Improveskin care effect efficacyVSAvoidpenetration speed and absorption efficiency
Core Design Contradiction:
ReliabilityVSSpeed

Solution Approach 1:

The patent incorporates penetration-enhancing auxiliary components (laurocapram, tetrahydropiperine, PEG-75 shea butter glycerides) that act as mediators to facilitate the delivery of active ingredients into the skin, enabling effective concentrations to reach target depths without compromising absorption efficiency

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The invention optimizes the concentration parameters of active ingredients within specific ranges (tetrahydrocurcumin 0.01-1%, ergothioneine 0.01-1%, phloretin 0.01-0.5%, retinol 0.01-0.1%) to balance efficacy with penetration capability, avoiding both under-dosing and over-concentration that would hinder absorption

Inventive Principle:
Principle #35Parameter changes

3Adaptability or versatility

If multiple active components are combined to address multiple skin concerns, then functional versatility is improved, but formulation complexity increases

Engineering Contradiction:
Improvefunctional versatility for multiple skin concernsVSAvoidformulation complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent designs a universal skin care composition that simultaneously addresses whitening, anti-inflammatory, anti-glycation, moisturizing, and anti-aging needs through a standardized multi-component formula, eliminating the need for multiple separate products and simplifying the user's skincare routine despite the complex ingredient profile

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition achieves significant inhibition of tyrosinase activity by 80-90%, reduces inflammatory factors TNF-α, IL-6, and IL-8 by 20-55%, and inhibits AGEs by 50%, while improving skin texture, brightness, and reducing acne colonization.

Implementation Method 1

The second auxiliary component can be any suitable auxiliary component that can cooperate with the first active component and/or promote the effect of the first active component

Methodology Applied
Scientific EffectPenetration enhancement: Permeation

Implementation Method 2

The composition achieves significant inhibition of tyrosinase activity by 80-90%

Methodology Applied
Scientific EffectEnzyme inhibition: Enzyme

Implementation Method 3

the first active component is selected from one or more of tetrahydrocurcumin, ergothioneine, phloretin, arbutin, resveratrol, vitamin C, dipotassium glycyrrhizinate, ceramide, Aloe vera polysaccharide, Opuntia dillenii polysaccharide, Astragali radix polysaccharide, Dendrobii caulis polysaccharide, Cucumis metuliferus polysaccharide, fucoidan, small-molecule hyaluronic acid

Methodology Applied
Scientific EffectHygroscopy: Absorption (physical)

Data Source

PatentUS20260069523A1Skin care composition and use thereof
Publication Date: 2026.03.12 NANJING NUTRABUILDING BIO TECH CO LTD
  • US20260069523A1 patent drawing
  • US20260069523A1 patent drawing
  • US20260069523A1 patent drawing

AI summary

The present invention discloses a skin care composition, comprising a first active component and a second auxiliary component. The first active component is selected from one or more of tetrahydrocurcumin, ergothioneine, phloretin, arbutin, resveratrol, vitamin C, dipotassium glycyrrhizinate, ceramide, Aloe vera polysaccharide, Opuntia dillenii polysaccharide, Astragali radix polysaccharide, Dendrobii caulis polysaccharide, Cucumis metuliferus polysaccharide, fucoidan, small-molecule hyaluronic acid, pearl powder, collagen, tea tree essential oil, thearubigins, salicylic acid, retinol, glycoxyl, carnosine; the second auxiliary component is selected from one or more of tetrahydropiperine, laurocapram, PEG-75 shea butter glycerides, hydrogenated castor oil, glycerol, lauric acid, sucrose laurate, butanediol, polysorbate, hydroxyethyl cellulose, 1,2-pentanediol, ethoxydiglycol. The skin care composition of the present invention can be used for whitening, anti-inflammatory, anti-glycation, moisturizing, skin firming, anti-bacterial and/or anti-aging.