Skin Disease Severity Analysis via Entropy Quantification

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Solution Overview

Problem

Current methods for assessing skin disease severity are subjective, inconsistent, and lack reproducibility, failing to provide a quantitative analysis that can effectively track disease progression and treatment effectiveness across various skin conditions.

Innovation Solution

A non-invasive method using digital imaging and a computer algorithm to quantify skin disease severity by calculating the entropy of skin images, comparing diseased skin to healthy skin, and providing a numerical score that reflects the level of randomness and disorder, applicable to various skin diseases.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If traditional visual inspection methods are used by physicians, then assessment can be performed quickly and simply, but the results are subjective and inconsistent

Engineering Contradiction:

Improvesimplicity of assessmentVSAvoidconsistency and reproducibility of results

Core Design Contradiction:

Ease of operationVSMeasurement precision

Solution Approach 1:

The patent replaces the mechanical/subjective visual inspection system with an automated image processing and entropy calculation system. Digital images of skin lesions are processed through algorithms that calculate entropy values, providing objective quantitative measurements that eliminate physician subjectivity while maintaining ease of operation through automated analysis.

Inventive Principle:

Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent transforms the assessment from qualitative visual parameters to quantitative entropy parameters. By calculating entropy values from skin lesion images, the system converts subjective visual assessments into objective numerical measurements that can be consistently reproduced and compared across different physicians and time points.

Inventive Principle:

Principle #35Parameter changes

2Measurement precision

If quantitative analysis methods are implemented, then measurement precision and objectivity are improved, but device complexity and time consumption increase

Engineering Contradiction:

Improveobjectivity of assessmentVSAvoidcomplexity of analysis system

Core Design Contradiction:

Measurement precisionVSDevice complexity

Solution Approach 1:

The patent replaces complex manual measurement and assessment procedures with automated computer-based image processing and entropy calculation algorithms. This substitution maintains high measurement precision and objectivity while reducing device complexity by using standard digital imaging equipment and automated software analysis rather than complex specialized instruments.

Inventive Principle:

Principle #28Mechanics substitution (Replace mechanical system)

3Measurement precision

If detailed visual assessment is performed, then measurement precision may be improved, but time consumption increases

Engineering Contradiction:

Improvedetail of assessmentVSAvoidtime for assessment

Core Design Contradiction:

Measurement precisionVSLoss of time

Solution Approach 1:

The patent replaces time-consuming detailed visual assessment with automated entropy calculation from digital images. The system quickly processes skin lesion images through entropy algorithms to provide detailed quantitative measurements without the time investment required for thorough manual visual inspection, thereby reducing assessment time while maintaining or improving measurement precision.

Inventive Principle:

Principle #28Mechanics substitution (Replace mechanical system)

Data Source

PatentUS11574405B2Analysis of the severity of skin disease through entropy quantification

Publication Date: 2023.02.07 DR MAKSYM BRESLAVETS MEDICINE PROFESSIONAL CORP

AI summary

The present invention provides an analysis and method of quantifying the severity of skin diseases through the skin exhibited entropy. Quantitative analysis and evaluation of skin is a new, non-invasive, quick, and reproducible method of assessing skin disease and skin disease progression. The quantitative analysis of the skin disease applies a entropy algorithm to quantify the severity of the disease and compared to healthy skin. The method is applied in determination of the severity of the skin disease or applied to determine the effectiveness of the subsequent treatment modalities. It is highly reproducible and removes physician's own bias and past experience.