Skin Microbiome Network Assessment for Personalized Cosmetics

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Solution Overview

Problem

Current network analysis methods for skin microbiomes are limited to studying population means and fail to reflect the unique microbiome of an individual, hindering personalized cosmetic composition development.

Innovation Solution

A method is developed to assess an individual's microbiome network by comparing it with a benchmark network, involving population and individual microbiome networks, to tailor personalized cosmetic compositions.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If population microbiome network analysis is used, then mean value across population can be studied, but individual-specific microbiome characteristics cannot be reflected

Engineering Contradiction:
Improveindividual microbiome assessment accuracyVSAvoidmicrobiome network analysis complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent segments the population microbiome network into individual-specific networks by subtracting the population mean network from each individual's observed network. This segmentation allows recovery of individual deviations from the population average, enabling precise individual assessment while maintaining the population-level framework.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent extracts individual-specific microbiome network characteristics by removing the population mean component from the observed network. This extraction isolates the individual-specific deviations and interactions, making them visible and measurable despite the complexity of the overall system.

Inventive Principle:
Principle #2Taking out (Extraction)

2Adaptability or versatility

If personalized cosmetic compositions are developed, then skin conditions can be targeted effectively, but requires complex individual microbiome profiling

Engineering Contradiction:
Improvepersonalization capabilityVSAvoidmicrobiome profiling complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent transforms the complex microbiome network data into a standardized set of parameters representing individual deviations from the population mean. These parameter changes simplify the data representation while preserving individual-specific information, making personalized composition development feasible without requiring overly complex profiling.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent establishes a feedback loop where individual microbiome network deviations are measured, cosmetic compositions are designed based on these deviations, and the effects are monitored. This feedback mechanism enables continuous refinement of personalized compositions while using manageable complexity in the profiling process.

Inventive Principle:
Principle #23Feedback

Data Source

PatentUS20250290158A1Method for assessing skin
Publication Date: 2025.09.18 CONOPCO INC
  • US20250290158A1 patent drawing

AI summary

Disclosed is a method of assessing skin comprising the steps of: A) identifying a first individual microbiome network of the desired skin surface of a person in need of skin assessment; B) comparing the first individual microbiome network with a benchmark individual microbiome network; and C) providing a cosmetic composition to change the first individual microbiome network toward the benchmark individual microbiome network.