Skin Microbiome Network Assessment for Personalized Cosmetics
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Solution Overview
Problem
Current network analysis methods for skin microbiomes are limited to studying population means and fail to reflect the unique microbiome of an individual, hindering personalized cosmetic composition development.
Innovation Solution
A method is developed to assess an individual's microbiome network by comparing it with a benchmark network, involving population and individual microbiome networks, to tailor personalized cosmetic compositions.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If population microbiome network analysis is used, then mean value across population can be studied, but individual-specific microbiome characteristics cannot be reflected
Solution Approach 1:
The patent segments the population microbiome network into individual-specific networks by subtracting the population mean network from each individual's observed network. This segmentation allows recovery of individual deviations from the population average, enabling precise individual assessment while maintaining the population-level framework.
Solution Approach 2:
The patent extracts individual-specific microbiome network characteristics by removing the population mean component from the observed network. This extraction isolates the individual-specific deviations and interactions, making them visible and measurable despite the complexity of the overall system.
2Adaptability or versatility
If personalized cosmetic compositions are developed, then skin conditions can be targeted effectively, but requires complex individual microbiome profiling
Solution Approach 1:
The patent transforms the complex microbiome network data into a standardized set of parameters representing individual deviations from the population mean. These parameter changes simplify the data representation while preserving individual-specific information, making personalized composition development feasible without requiring overly complex profiling.
Solution Approach 2:
The patent establishes a feedback loop where individual microbiome network deviations are measured, cosmetic compositions are designed based on these deviations, and the effects are monitored. This feedback mechanism enables continuous refinement of personalized compositions while using manageable complexity in the profiling process.
Data Source
AI summary
Disclosed is a method of assessing skin comprising the steps of: A) identifying a first individual microbiome network of the desired skin surface of a person in need of skin assessment; B) comparing the first individual microbiome network with a benchmark individual microbiome network; and C) providing a cosmetic composition to change the first individual microbiome network toward the benchmark individual microbiome network.
