Skin Abnormality Risk Assessment Using Longitudinal Image Alignment

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Solution Overview

Problem

Conventional machine learning models for skin abnormality detection struggle to differentiate between new, high-risk abnormalities and known, stable features, leading to false positives due to a lack of historical memory and context awareness, and are prone to misinterpret benign variations caused by changes in image capture conditions.

Innovation Solution

A context-aware, longitudinally-trained skin abnormality detection model that uses spatially aligned, historical image data with user annotations to understand feature progression and account for image capture conditions, enabling accurate risk assessment.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional machine learning models are used for skin abnormality detection, then the system can identify features in captured images, but it cannot differentiate between new high-risk abnormalities and known stable features, leading to false positives

Engineering Contradiction:
Improveabnormality detection accuracyVSAvoidfalse positive rate
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The system performs preliminary action by capturing and storing historical skin images before the current assessment. The machine learning model compares the current skin feature against previously captured images to determine if the feature is new or pre-existing. This preliminary historical data collection enables the system to differentiate between new high-risk abnormalities and stable chronic features, reducing false positives while maintaining detection accuracy.

Inventive Principle:
Principle #10Preliminary action

2Productivity

If simple feature-detection models are used, then the system can identify skin features, but it lacks historical memory and repeatedly flags stable features as problems, causing alert fatigue

Engineering Contradiction:
Improvedetection speedVSAvoidclinical confidence
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The system implements feedback by continuously comparing current skin images with historical images and using the results to adjust alert generation. The machine learning model learns from past assessments and incorporates historical context into current evaluations. This feedback mechanism allows the system to maintain fast detection speed while improving clinical confidence by reducing repeated false alerts about stable features.

Inventive Principle:
Principle #23Feedback

3Device complexity

If the model does not account for image capture conditions, then the analysis is simpler, but it misinterprets benign variations caused by lighting or positioning as clinical changes

Engineering Contradiction:
Improvemodel complexityVSAvoidchange detection accuracy
Core Design Contradiction:
Device complexityVSMeasurement precision

Solution Approach 1:

The system applies parameter changes by incorporating image capture context data (lighting conditions, device positioning, capture angle) as additional input parameters to the machine learning model. The model learns to recognize and compensate for variations caused by these parameters, distinguishing between benign variations due to capture conditions and true clinical changes. This approach improves measurement precision while maintaining manageable model complexity through efficient feature engineering.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS20260069199A1Method and system for predictive risk assessment of skin abnormalities
Publication Date: 2026.03.12 BLUEDROP MEDICAL LTD
  • US20260069199A1 patent drawing
  • US20260069199A1 patent drawing
  • US20260069199A1 patent drawing

AI summary

A method for assessing a risk associated with a skin abnormality is disclosed. The method involves using a skin abnormality detection model to analyze a current image dataset captured by a skin inspection device to identify a current instance of a feature of interest and determine an associated risk level. The model is trained using a process that generates enriched training data. The process comprises receiving user-generated annotations for a feature of interest across a series of historical image datasets captured over time. These historical datasets are aligned using an image registration process to establish a consistent anatomical location for the feature. A set of training data records is then generated, with each record comprising an annotation, a set of image acquisition parameters used for the corresponding image, and data defining the consistent anatomical location. The skin abnormality detection model is subsequently trained using this set of training data records.