Slew Rate Detection in Wireless Cardiac Pacing Receivers

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Solution Overview

Problem

Conventional implantable wireless electrodes fail to distinguish between ultrasound energy signals intended for cardiac pacing and those used for diagnostic or therapeutic purposes, leading to unintended stimulation of the heart during procedures like ultrasound imaging.

Innovation Solution

The implementation of a receiver-stimulator system with a circuit that includes a slew rate detector and pulse duration detector to differentiate between cardiac pacing signals and other ultrasound energy signals, blocking or limiting signals with rates or durations outside predetermined thresholds from being delivered to the heart.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If a wireless electrode is used to receive ultrasound energy for cardiac pacing, then effective endocardial pacing is achieved, but unintended stimulation occurs during diagnostic ultrasound procedures

Engineering Contradiction:
Improvecardiac pacing effectivenessVSAvoidunintended heart stimulation
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent applies parameter changes by monitoring the slew rate (rate of change of voltage) and pulse duration of received ultrasound signals. Cardiac pacing signals have specific slew rate and duration parameters that differ from diagnostic ultrasound signals. By detecting these parameter differences, the device can distinguish between intended pacing signals and unintended diagnostic signals, preventing inappropriate stimulation while maintaining effective pacing therapy.

Inventive Principle:
Principle #35Parameter changes

2Adaptability or versatility

If the wireless electrode responds to all ultrasound signals, then it can be activated by any ultrasound source, but it cannot distinguish between pacing and diagnostic signals

Engineering Contradiction:
Improveultrasound signal responsivenessVSAvoidsignal differentiation accuracy
Core Design Contradiction:
Adaptability or versatilityVSMeasurement precision

Solution Approach 1:

The device maintains adaptability by responding to ultrasound signals in general but improves measurement precision by specifically measuring the slew rate and pulse duration parameters. These parameter measurements enable accurate differentiation between cardiac pacing signals and diagnostic ultrasound signals, allowing the electrode to selectively respond only to appropriate pacing signals while ignoring diagnostic signals.

Inventive Principle:
Principle #35Parameter changes

3Ease of operation

If diagnostic ultrasound procedures are performed on patients with implanted wireless electrodes, then cardiac function can be assessed, but the ultrasound energy may inadvertently stimulate the heart

Engineering Contradiction:
Improvediagnostic procedure availabilityVSAvoidinadvertent cardiac stimulation
Core Design Contradiction:
Ease of operationVSObject-affected harmful factors

Solution Approach 1:

The patent implements feedback by continuously monitoring the characteristics of received ultrasound signals and using this information to control the switching element. When the monitored slew rate and pulse duration match those of cardiac pacing signals, the switching element enables stimulation. When they match diagnostic ultrasound characteristics, the switching element blocks stimulation. This feedback mechanism allows diagnostic procedures to be performed safely while preventing inadvertent cardiac stimulation.

Inventive Principle:
Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Effectively prevents unintended electrical stimulation of the heart by accurately distinguishing between cardiac pacing signals and diagnostic or therapeutic ultrasound signals, ensuring synchronized heartbeat therapy without interference from external ultrasound procedures.

Implementation Method 1

a piezoelectric element that is enclosed by a housing and produces voltage signals delivered to the patient's body in response to receiving ultrasound energy

Methodology Applied
Scientific EffectPiezoelectric effect: Piezoelectric Effect

Data Source

PatentEP3785761B1Pulse delivery device including slew rate detector, and associated systems
Publication Date: 2024.02.07 EBR SYSTEMS INC
  • EP3785761B1 patent drawingFigure 1
  • EP3785761B1 patent drawingFigure 2A~2C
  • EP3785761B1 patent drawingFigure 3

AI summary

The present technology is generally directed to implantable medical device systems configured to provide cardiac resynchronization therapy. In some embodiments, the implantable medical device system comprises a housing, electrodes carried by the housing, a transducer configured to produce input voltage signals in response to ultrasound energy, and a circuit configured to provide, via an electrical pathway, output voltage signals based on the input voltage signals. The circuit comprises a movable switch, and a slew rate detector configured to detect whether a voltage rate of an individual pulse of the input voltage signals exceeds a predetermined threshold voltage rate. The circuit is configured to move the switch to an open position in response to the detected voltage rate exceeding the predetermined threshold voltage rate.