Slide Preparation Alignment for Consistent Sample Deposition
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Solution Overview
Problem
The positioning of samples on microscope slides for automated processing is inconsistent, affecting the smearing and examination of liquid or other samples.
Innovation Solution
A slide preparation apparatus with a support surface, slide channel, fiducial mark, guide groove, and sample tube holder is designed to align and secure the slide, ensuring precise sample deposition.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Manufacturing precision
If hand positioning of samples on slides is used, then ease of operation is maintained, but manufacturing precision of sample position deteriorates
Solution Approach 1:
The apparatus divides the slide preparation process into distinct functional zones: a slide channel for holding slides, a fiducial mark system for positioning, and a sample tube holder for sample deposition. This segmentation allows each component to perform its specific function precisely while maintaining overall system simplicity.
Solution Approach 2:
The fiducial mark acts as an intermediary element between the slide channel and the sample tube holder, providing a visual and physical reference point that mediates the alignment process. This intermediary enables precise sample positioning without requiring complex automated positioning systems.
2Productivity
If automated slide processing is implemented, then productivity is improved, but manufacturing precision of sample position deteriorates due to lack of consistent positioning
Solution Approach 1:
The apparatus performs preliminary positioning actions by pre-placing the fiducial mark at a defined distance from the stop in the slide channel, and pre-configuring the sample tube holder to align with the fiducial mark. This preliminary arrangement ensures that when samples are deposited, they automatically land at the correct position, enabling consistent automated processing.
Solution Approach 2:
The patent replaces complex mechanical positioning systems with a simple geometric alignment system based on the fiducial mark and guide groove. This substitution allows automated processing to achieve precise sample positioning through visual alignment rather than complex mechanical control.
3Manufacturing precision
If fiducial mark and guide groove alignment system is added, then manufacturing precision of sample position is improved, but device complexity increases
Solution Approach 1:
The patent merges the fiducial mark, guide groove, and sample tube holder into a single integrated alignment system. These components work together as a unified positioning mechanism, achieving precise sample deposition without requiring multiple separate positioning devices or complex assembly procedures.
Data Source
AI summary
Various examples are provided related to slide preparation. In one example, a slide preparation apparatus includes a support surface, an upper surface opposite the support surface, and a sample tube holder. The upper surface can include a slide channel extending to a stop, a fiducial mark disposed in the slide channel, and a support bar extending across the slide channel. The sample tube holder can secure a sample tube in a vertical position adjacent to an end of the upper surface adjacent to the stop. When a syringe is supported by a sample tube positioned in the sample tube holder, a needle of the syringe can be aligned with the fiducial mark when it is seated in a guide groove of the support bar.