Smart Blister Packaging With Impedance Tracking for Medication Adherence

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Solution Overview

Problem

Poor adherence to medication regimens, particularly with oral contraceptive pills, leads to unintended pregnancies, resulting in significant healthcare costs and compromised health outcomes, as existing reminder systems are not effective in ensuring consistent medication intake.

Innovation Solution

A modular smart case with an electronics module and detection module that tracks the state of blister cards using electrical impedance tomography, providing real-time adherence monitoring and alerts through a connected smartphone app.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If automated reminder notifications are delivered through mobile devices, then medication adherence is improved, but device complexity and user dependency increase

Engineering Contradiction:
Improvemedication adherenceVSAvoidsystem complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The smart packaging system performs self-monitoring of medication dispensing through integrated sensors that automatically detect when medication is removed from the package, eliminating the need for manual user reporting and reducing dependency on external mobile devices for tracking

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent introduces an intermediary monitoring system between the medication package and the user, where sensors embedded in the packaging serve as intermediaries to automatically detect and report dispensing events, reducing the complexity burden on end-users

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If smart packaging with sensor arrays is implemented, then medication dispensing monitoring is improved, but manufacturing complexity increases

Engineering Contradiction:
Improvedispensing monitoring accuracyVSAvoidpackaging manufacturing
Core Design Contradiction:
Measurement precisionVSEase of manufacture

Solution Approach 1:

The patent combines multiple functions (sensor array, communication module, power management) into an integrated smart packaging unit that is manufactured as a single assembly, reducing the number of separate components that need to be assembled and simplifying the overall manufacturing process despite the advanced functionality

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The smart packaging system is designed with multi-functional components that serve multiple purposes: the sensor array monitors dispensing, the communication module transmits data, and the power management system handles energy distribution, allowing a single manufacturing process to produce a highly functional integrated unit

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Reliability

If real-time adherence tracking is implemented, then health outcomes are improved, but data privacy concerns increase

Engineering Contradiction:
Improvehealth outcome achievementVSAvoiddata privacy risks
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent implements local data processing where adherence information is processed and stored within the immediate packaging system or on the user's personal device rather than being continuously transmitted to external servers, minimizing exposure to data privacy risks while maintaining local accountability for health outcomes

Inventive Principle:
Principle #3Local quality

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system significantly improves medication adherence by providing accurate tracking and reminders, reducing unintended pregnancies and associated healthcare costs by ensuring consistent medication intake.

Implementation Method 1

The detection module comprises a sensor array that includes a substrate having a platen and an array of through-holes... Each sensor of the sensor array includes a pair of electrical contacts that are located on either side of its respective through-hole and configured to electrically couple with the lidding film. The electrical contact are configured to measure the impedance across the dispensing region of its respective reservoir.

Methodology Applied
Scientific EffectElectrical Impedance Tomography: Electrical Impedance Tomography

Data Source

PatentUS11913893B2Smart packaging for improved medication regimen compliance
Publication Date: 2024.02.27 DOSECALL LLC
  • US11913893B2 patent drawing
  • US11913893B2 patent drawing
  • US11913893B2 patent drawing

AI summary

The present disclosure enables apparatus and methods for tracking medications and/or product units via smart-packaging concepts. Embodiments include sensors that monitor the state of a blister-card package having an unpatterned lidding film by measuring the impedance of each dispensing region of the lidding film that defines a portion of a blister. In some embodiments, the impedance is measured via a plurality of contact points arranged on opposite sides of each dispensing region, where the contact points are resistively or capacitively coupled with the lidding film. In some embodiments, the impedance map of a measurement region on the blister card is derived via electrical impedance tomography or electrical resistance tomography, where the measurement region includes a plurality of dispensing regions.