Smartphone Retinal Imaging Real-Time Panorama Stitching

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Solution Overview

Problem

Capturing wide-field retinal images is challenging due to the need for precise alignment and stability, which is difficult to achieve with handheld systems like smartphones, and traditional methods require post-image acquisition processing to construct panoramas, leading to potential inadequacies in image quality detection after patient exams.

Innovation Solution

A system and method using a smartphone camera with associated optics to capture a digital video stream of retinal images, process them in real-time to identify points of interest, determine overlapping alignments, and combine images into a panorama, allowing for real-time construction of a wide-field retinal image with quality assessment and discarding of lower quality frames.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If handheld smartphone-based imaging systems are used, then portability and cost are improved, but alignment precision and image quality are worsened

Engineering Contradiction:
ImproveportabilityVSAvoidalignment precision
Core Design Contradiction:
Ease of operationVSMeasurement precision

Solution Approach 1:

The system performs preliminary actions by capturing multiple video frames and identifying points of interest (blood vessels, optic disc) before final image assembly. This preliminary processing allows the system to pre-determine alignment relationships and compensate for handheld instability, achieving good alignment precision without requiring a stationary tabletop setup.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system implements feedback by continuously analyzing video frames to track the position of retinal features and dynamically adjusting the panorama construction algorithm. This real-time feedback mechanism allows the system to compensate for hand movements and maintain alignment precision throughout the examination, resolving the contradiction between handheld portability and alignment accuracy.

Inventive Principle:
Principle #23Feedback

2Area of stationary object

If wider field of view is implemented, then diagnostic capability is improved, but alignment precision requirements increase

Engineering Contradiction:
Improvefield of viewVSAvoidalignment precision
Core Design Contradiction:
Area of stationary objectVSMeasurement precision

Solution Approach 1:

The system segments the wide field of view into multiple overlapping video frames captured sequentially. Each frame is processed independently to identify points of interest, and then these segmented frames are stitched together using feature matching. This segmentation approach allows the system to achieve a wide overall field of view while maintaining alignment precision within each individual frame, as the alignment burden is distributed across multiple smaller, more manageable segments.

Inventive Principle:
Principle #1Segmentation

3Loss of time

If post-image acquisition panorama construction is used, then processing time is reduced, but image quality assurance is worsened

Engineering Contradiction:
Improveprocessing timeVSAvoidimage quality assurance
Core Design Contradiction:
Loss of timeVSReliability

Solution Approach 1:

The system performs preliminary quality assessment during the image acquisition phase by analyzing each video frame as it is captured. Points of interest are identified and quality metrics are calculated in real-time, allowing the system to pre-select the best frames for panorama construction. This preliminary action ensures image quality assurance is maintained while minimizing post-processing time, as poor quality frames are identified and discarded during acquisition rather than requiring extensive post-exam evaluation.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentEP3086705B1Wide field retinal image capture system and method
Publication Date: 2020.04.22 RSBV LLC
  • EP3086705B1 patent drawingFigure 1
  • EP3086705B1 patent drawingFigure 2
  • EP3086705B1 patent drawingFigure 3~4

AI summary

A method, system or apparatus for generating a wide field retinal image. System embodiments comprise a camera, which may be a smartphone camera and associated optics to capturing a digital video stream of individual retinal images and store the video stream of individual retinal images in a memory associated with the camera. The system or method then implements the steps of processing each retinal image and combining selected retinal images into a panorama in real time, during an ocular examination.