Smear Staining Machine Viscosity-Based Parameter Control
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Solution Overview
Problem
Conventional smear staining machines adjust smearing parameters based on Hematocrit (HCT) value, which is inadequate for representing the characteristics of blood samples, especially for abnormal samples with low HCT values, leading to improper smear parameters and affected blood film processing due to environmental and storage conditions.
Innovation Solution
A smear control method that determines smearing parameters based on the viscosity of the test sample by measuring the relative viscosity of the sample and a reference fluid, using a pressure sensor and temperature sensor to calculate the viscosity ratio, allowing for precise configuration of smearing parameters such as blood drop volume, smearing speed, and smearing angle.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If smearing parameters are adjusted based on HCT value, then the control method is simple, but the accuracy of representing blood sample characteristics deteriorates
Solution Approach 1:
The patent changes the control parameter from HCT value to viscosity value. Viscosity is measured by detecting the pressure difference across a flow resistance element, providing a more comprehensive representation of blood sample characteristics that accounts for environmental and storage conditions. This parameter change resolves the contradiction by maintaining measurement accuracy while keeping the control method relatively simple through automated viscosity-based parameter adjustment.
2Ease of operation
If HCT value is used for guiding smear parameters, then the control process is straightforward, but the reliability deteriorates under varying environmental conditions
Solution Approach 1:
The patent replaces HCT value with viscosity value as the guiding parameter. Viscosity measurement through pressure difference detection provides a more reliable indicator that reflects the actual flow characteristics of the blood sample under current environmental conditions. This ensures consistent and reliable smear parameter guidance regardless of temperature, humidity, or storage condition variations.
3Measurement precision
If viscosity measurement is implemented, then the accuracy of blood sample characterization improves, but the device complexity increases
Solution Approach 1:
The patent replaces complex mechanical viscosity measurement systems with an electronic pressure difference detection system. By using a flow resistance element and pressure sensors to measure the pressure difference during sample flow, the system achieves accurate viscosity characterization without requiring complex mechanical viscometers, thereby improving measurement precision while limiting device complexity increase.
4Manufacturing precision
If viscosity-based control is used, then the smearing effect improves, but the measurement and control complexity increases
Solution Approach 1:
The patent uses electronic pressure difference measurement instead of complex mechanical measurement systems to achieve accurate viscosity-based control. This substitution improves blood film processing quality through precise viscosity measurement while keeping the control system relatively simple through automated electronic control and processing of pressure difference signals.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach provides a more accurate representation of the blood sample characteristics, reducing the influence of environmental and storage conditions, and improving the smearing process by using the viscosity of the sample to guide parameter configuration, resulting in better smearing effects.
Implementation Method 1
measuring a viscosity characteristic of the test sample when the test sample flows through a pipeline under a preset condition
Implementation Method 2
the viscosity characteristic is a physical quantity influenced by the viscosity of the test sample when the test sample flows, and the physical quantity is a function of viscosity
Data Source
AI summary
A smear staining machine and a smearing control method and device thereof. The viscosity of the test sample is used for guiding the configuration of at least on smearing parameter. Since the viscosity of the test sample presents multiple influences of many effecting parameters, it is more suitable for presenting the characteristics of the test sample. Therefore, better smearing effect could be acquired by referring the viscosity of the test sample to get the smearing parameter.