SNP-Mapped IV and IM Nutrition Formula Creation With Patient Feedback
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Solution Overview
Problem
Current IV and IM nutrition therapies use generic formulations that do not account for individual genetic and medical differences, leading to suboptimal supplementation and less effective therapy.
Innovation Solution
A method and system for creating genetically personalized IV and IM nutrition therapy formulas by mapping micronutrients to SNPs, symptoms, and therapeutic objectives using scientific literature and patient feedback to develop custom formulas tailored to individual needs.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Adaptability or versatility
If generic formulations are used for IV and IM nutrition therapy, then the therapy can be administered to all patients uniformly, but the therapy does not account for individual genetic and medical differences, leading to suboptimal supplementation
Solution Approach 1:
The patent segments the nutrition therapy formulation process into distinct functional modules: a database storing scientific literature and treatment outcomes, a mapping system that links micronutrients to SNPs/symptoms/conditions, a formula creation algorithm that processes patient data, and a feedback mechanism that updates the database. This segmentation allows the system to handle complex personalized formulations through manageable, modular components.
Solution Approach 2:
The patent introduces an intermediary mapping system that connects micronutrients to genetic markers (SNPs), symptoms, conditions, and therapeutic objectives. This mapping acts as a mediator between raw patient data and the final personalized formula, enabling the system to translate complex genetic and medical information into specific nutritional recommendations without requiring direct complex analysis for each patient.
Solution Approach 3:
The patent utilizes parameter changes by dynamically adjusting micronutrient dosages and compositions based on patient-specific parameters such as SNP profiles, symptom severity, medical conditions, and treatment responses. The system modifies formulation parameters (micronutrient types and amounts) according to varying patient parameters, enabling personalized therapy while maintaining a standardized system framework.
2Measurement precision
If personalized formulas are created based on genetic data and medical information, then the therapy addresses individual needs more accurately, but the process requires complex mapping and scoring systems
Solution Approach 1:
The system performs self-service by automatically processing patient genetic data, medical information, and symptom profiles through the mapping system and algorithm to generate personalized formulas without requiring manual expert analysis. The database and algorithm work autonomously to match patients with appropriate micronutrient formulations based on pre-established scientific literature and outcome data.
Solution Approach 2:
The patent implements a feedback mechanism where treatment outcomes from previous patients are stored in the database and used to refine and update the mapping system and algorithm. This feedback loop continuously improves the precision of micronutrient matching by incorporating real-world treatment results, allowing the system to learn and adapt while maintaining automated operation.
3Reliability
If generic formulations are used, then the administration process is simple and quick, but the therapy provides excess unnecessary nutrients or omits vital ingredients
Solution Approach 1:
The patent applies preliminary action by pre-processing and storing extensivescientific literature, treatment outcomes, and micronutrient-SNP-symptom-condition relationships in the database before patient treatment begins. The mapping system and algorithm are pre-configured with this knowledge, enabling rapid generation of personalized formulas when patient data is provided, thus reducing the time required at the point of care while ensuring accurate, evidence-based formulations.
Data Source
AI summary
A method of creating a genetically personalized intravenous or intramuscular nutrition therapy treatment formula includes developing an initial mapping of individual micronutrients to SNPs, symptoms, conditions, and therapeutic objectives based on existing individual scientific literature references that link the specific micronutrient to an SNP, a symptom, a condition, or a therapeutic objective. The method includes receiving an SNP and a symptom, a condition, or a therapeutic objective for a patient, comparing the SNP, symptom, condition, therapeutic objective combination with the initial mapping to identify matching micronutrients, creating a custom treatment formula with the identified micronutrients, and treating the patient with the formula. Feedback data about the formula's effectiveness is received and the initial mapping is updated to account for the feedback data. This process is repeated for subsequent patients positioned geographically remotely from each other so that future patients are treated with reference to an updated current mapping.