Social Media Side-Effect Tracking via NLP

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Solution Overview

Problem

Current methods for identifying and tracking drug side-effects are limited by small sample sizes in clinical trials and reliance on busy healthcare professionals, leading to incomplete and inefficient post-market monitoring.

Innovation Solution

A system utilizing natural language processing, including side-effect recognizers, relationship extractors, and reporting systems, that aggregates data from social media to identify and track adverse effects associated with substances, leveraging recurrent neural networks and distributed databases for efficient data management.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If clinical trials are conducted with limited patient numbers to comply with regulatory requirements, then the trial can be completed efficiently, but the reliability of side-effect identification deteriorates

Engineering Contradiction:
Improveclinical trial completion efficiencyVSAvoidside-effect identification reliability
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent introduces social media data as an intermediary source to bridge the gap between limited clinical trial data and comprehensive side-effect identification. The system uses NLP processors to extract side-effect information from social media platforms, creating an additional data channel that complements traditional clinical trials and enhances detection reliability without extending trial duration

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent transitions from a single-dimension approach (clinical trials only) to a multi-dimensional approach by incorporating social media data from different platforms and sources. This dimensional expansion allows the system to gather side-effect information from diverse user experiences, thereby improving identification reliability while maintaining efficient trial completion

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Device complexity

If drug companies rely on healthcare professionals to report side-effects after drug approval, then the reporting system is simple to maintain, but the completeness of side-effect tracking deteriorates due to professionals being busy with other tasks

Engineering Contradiction:
Improvereporting system complexityVSAvoidside-effect information completeness
Core Design Contradiction:
Device complexityVSLoss of information

Solution Approach 1:

The patent enables patients to self-report side-effects directly through social media platforms without requiring healthcare professionals to manually collect and submit reports. The NLP system automatically processes these self-generated reports, extracting side-effect information and relating it to specific drugs, thereby maintaining simple system architecture while dramatically improving information completeness

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent replaces the manual mechanical process of healthcare professionals reporting side-effects with an automated NLP-based system that processes social media data. This substitution eliminates the bottleneck of professional availability while maintaining reporting simplicity through automated data extraction and analysis

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Loss of information

If social media data is processed to identify side-effects, then the comprehensiveness of side-effect tracking is improved, but the memory usage and data processing complexity increase

Engineering Contradiction:
Improveside-effect information completenessVSAvoiddata processing system complexity
Core Design Contradiction:
Loss of informationVSDevice complexity

Solution Approach 1:

The patent segments the social media data processing task into distinct functional modules: data collection from multiple platforms, NLP processing for side-effect identification, relationship extraction for drug-side effect associations, and result aggregation. This segmentation manages complexity by organizing processing steps into manageable, independent components while maintaining comprehensive side-effect tracking

Inventive Principle:
Principle #1Segmentation

4Reliability

If extensive research and clinical trials are conducted to identify side-effects, then the reliability of side-effect identification is improved, but the time and resources required increase

Engineering Contradiction:
Improveside-effect identification reliabilityVSAvoidresearch and trial duration
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent performs preliminary action by continuously monitoring and analyzing social media data before and during clinical trials. This ongoing preliminary analysis allows the system to identify potential side-effects early, enabling faster decision-making and reducing the overall time required for extensive research and trial processes while maintaining identification reliability

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS10762169B2System and method for determining side-effects associated with a substance
Publication Date: 2020.09.01 ACCENTURE GLOBAL SOLUTIONS LTD
  • US10762169B2 patent drawing
  • US10762169B2 patent drawing
  • US10762169B2 patent drawing

AI summary

A system for determining adverse effects associated with a substance includes a side-effect recognizer, a relationship extractor, a processor, and a reporting system. The side-effect recognizer utilizes a first recurrent neural network (RNN) to identify a first portion of received data associated with an adverse effect to thereby determine the adverse effect associated with the received data. The relationship extractor utilizes a second RNN to identify a second portion of the received data associated with a substance and a third portion of the received data that indicates a relationship between the substance and the adverse effect to thereby determine the substance associated with the received data and the relationship between the substance and the adverse effect. The processor is in communication with the adverse effect recognizer and the substance relationship extractor and aggregates and relates the adverse effect, substance, and relationship. The reporting system is in communication with the processor and generates a report to convey the relationship between the substance and the adverse effect.