Solanum Extract Anti-Wart Composition
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Solution Overview
Problem
Current treatments for warts, such as topical therapies, laser treatments, and cryotherapy, are often ineffective for all types of warts and can cause severe side effects like pain, ulceration, and scarring, making them unsuitable for all patients, especially children.
Innovation Solution
A water-soluble extract from the Solanum genus, comprising solamargine and solasonine, is used to treat warts, prepared through an acidic aqueous extraction process, which is effective in treating cutaneous, mucosal, common, flat, and plantar warts without causing adverse side effects.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If topical therapy is used to treat warts, then the treatment can be applied to various wart types, but the treatment effectiveness is insufficient and recurrence occurs
Solution Approach 1:
The patent changes the chemical parameters of the treatment by using a water-soluble extract containing specific concentrations of solamargine and solasonine (at least 60 wt% combined) instead of conventional topical agents. This parameter change in chemical composition provides both effective wart treatment and prevents recurrence, resolving the contradiction between treatment effectiveness and recurrence prevention.
2Reliability
If laser treatment or cryotherapy is used to treat warts, then the treatment can achieve good therapeutic effect, but severe side effects occur such as pain, ulceration, and scarring
Solution Approach 1:
The patent introduces a water-soluble plant extract as an intermediary substance that mediates between the need for effective wart treatment and the avoidance of severe side effects. This natural extract containing solamargine and solasonine provides therapeutic effect without causing pain, ulceration, or scarring associated with laser and cryotherapy methods.
3Reliability
If conventional treatments are used on children, then the treatment can address the wart condition, but children refuse treatment due to unendurable severe side effects
Solution Approach 1:
The patent changes the physical and chemical parameters of the treatment formulation by using a water-soluble extract that can be applied topically without causing severe pain or discomfort. This parameter change in the treatment's physical properties (water solubility, gentle formulation) makes the treatment acceptable to children while maintaining efficacy.
Data Source
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AI summary
Disclosed herein is an anti-wart pharmaceutical composition including a water-soluble extract from a plant of Solanum genus, the water-soluble extract comprising solamargine and solasonine. Also disclosed is the use of the water-soluble extract in the manufacture of a medicament for treating wart.