Solid Antiviral Composition with Organic Acid and Silica Substrate
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Solution Overview
Problem
Current antiviral compositions fail to provide both rapid and persistent antiviral effectiveness against viruses like rhinoviruses and rotaviruses, as they often rely on volatile alcohols that evaporate quickly, lacking a persistent barrier layer on surfaces.
Innovation Solution
A solid antimicrobial composition comprising a powdered solid substrate, such as hydrated silica, combined with a virucidally effective organic acid, which forms a residual layer on surfaces to inactivate or destroy viruses, including nonenveloped and influenza viruses, without the need for rinsing.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Speed
If volatile alcohols are used as the active ingredient, then rapid antiviral effectiveness is achieved, but persistent antiviral activity is lost due to quick evaporation
Solution Approach 1:
The patent changes the physical state of the alcohol from liquid to solid by forming a solid solution with a solid substrate. This parameter change allows the alcohol to maintain its antiviral efficacy while eliminating the evaporation problem, thus providing both rapid and persistent antiviral activity.
Solution Approach 2:
The patent creates a composite material consisting of alcohol molecules embedded within a solid substrate matrix. This composite structure combines the antiviral properties of alcohol with the stability and persistence of solid materials, resolving the contradiction between rapid action and duration of effect.
2Productivity
If a liquid antiviral composition is applied, then rapid virus inactivation occurs, but a persistent barrier layer is not formed on the surface
Solution Approach 1:
The patent changes the physical state of the composition from liquid to solid, enabling it to form a persistent barrier layer on surfaces. The solid composition maintains contact with the surface without running off or evaporating, while still delivering rapid virus inactivation through the embedded alcohol molecules.
Solution Approach 2:
The solid substrate acts as an intermediary carrier that delivers the antiviral alcohol to viral particles. The substrate provides a persistent presence on the surface, mediating continuous antiviral protection while the alcohol molecules perform the actual virus inactivation function.
3Reliability
If traditional antiviral compositions are used, then virus destruction is achieved, but the composition lacks residual antiviral activity after application
Solution Approach 1:
The patent incorporates the antiviral alcohol into the solid substrate in advance, creating a pre-loaded delivery system. When applied to surfaces, the composition provides immediate virus destruction while the solid matrix ensures prolonged presence, delivering preliminary and sustained protection simultaneously.
Solution Approach 2:
The solid composition enables continuous antiviral action by maintaining persistent contact with the surface. The alcohol molecules remain available in the solid matrix over time, providing uninterrupted virus destruction capability rather than a single instantaneous effect.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composition achieves a substantial, broad-spectrum antiviral activity with a persistent effect, maintaining antiviral efficacy for several hours by forming a continuous film on treated surfaces, effectively controlling virus transmission and reducing infection risk.
Implementation Method 1
an organic acid. The combination of (a) and (b) provides a solid composition that, when applied directly to a surface, can inactivate or destroy viruses
Implementation Method 2
a powdered solid substrate... forms a residual layer on surfaces to inactivate or destroy viruses
Data Source
AI summary
Antiviral compositions having a rapid antiviral effectiveness, and a persistent antiviral effectiveness, are disclosed. The antimicrobial compositions contain (a) a powdered solid substrate and (b) an organic acid.