Solid Enzymatic Detergent Composition for Spill-Safe Instrument Cleaning

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Solution Overview

Problem

Existing enzymatic detergents are predominantly liquid, posing stability and spillage risks, and are difficult to incorporate into solid compositions while maintaining efficacy, particularly for cleaning medical and dental instruments and ware.

Innovation Solution

Development of stable solid enzymatic detergent compositions comprising alkali metal carbonate, acid, and surfactant, which form a solidification matrix, allowing enzymes like proteases, amylases, and cellulases to maintain efficacy in solid form, with pH adjustment to near neutral to moderately alkaline ranges.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Object-affected harmful factors

If enzymes are incorporated into solid detergent compositions, then packaging and safety concerns related to spillage are reduced, but enzyme stability and efficacy are compromised

Engineering Contradiction:
Improvespillage riskVSAvoidenzyme efficacy
Core Design Contradiction:
Object-affected harmful factorsVSReliability

Solution Approach 1:

The patent changes the physical state parameter of the detergent from liquid to solid form while adjusting pH parameters to near neutral to moderately alkaline ranges (pH 6-11 upon dilution), enabling enzyme incorporation into solid compositions without compromising stability or efficacy. This is achieved through careful selection of alkaline builders and buffering systems that maintain optimal pH for enzyme activity in solid format.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent creates a composite solid detergent composition combining multiple components including enzymes, alkaline builders (carbonates, silicates), surfactants, and buffering agents. This composite structure allows the solid formulation to maintain both structural integrity for spill-free handling and chemical conditions necessary for enzyme activity, resolving the contradiction between solid form stability and enzyme efficacy.

Inventive Principle:
Principle #40Composite materials

2Volume of stationary object

If enzymes are incorporated into solid detergent compositions, then packaging volume is reduced, but formulation complexity increases

Engineering Contradiction:
Improvepackaging volumeVSAvoidformulation complexity
Core Design Contradiction:
Volume of stationary objectVSDevice complexity

Solution Approach 1:

The patent merges multiple functional components into a single solid detergent composition: enzymes for soil breakdown, alkaline builders for pH maintenance and water softening, surfactants for emulsification, and buffering agents for pH stability. This consolidation achieves space-efficient packaging while managing formulation complexity through synergistic component selection where each ingredient serves multiple functions.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The solid detergent composition is designed with multi-functional ingredients that perform multiple roles. For example, alkaline builders provide both pH control and water softening, while buffering agents maintain pH stability and enhance enzyme activity. This multi-functionality reduces the number of separate components needed, simplifying the overall formulation despite the solid state requirements.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Reliability

If liquid enzymatic detergents are used, then enzyme activity is maintained, but stability and spillage risks increase

Engineering Contradiction:
Improveenzyme activityVSAvoidcomposition stability
Core Design Contradiction:
ReliabilityVSStability of the object's composition

Solution Approach 1:

The patent transforms the composition from liquid to solid state while adjusting pH parameters to ranges optimal for enzyme stability and activity (pH 6-11 upon dilution). This parameter change enables the formulation to achieve both composition stability for spill-free handling and maintained enzyme activity through careful selection of alkaline builders and buffering systems.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The solid detergent composition is designed as a stable, shelf-ready product that eliminates the need for complex liquid formulations requiring special containers and spill prevention measures. The solid format provides inherent stability and safety, making the product more reliable for storage and handling while maintaining enzyme efficacy until use.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solid enzymatic detergents provide effective cleaning of medical and dental instruments and ware by breaking down soils like blood and protein, while reducing packaging and safety concerns associated with liquid detergents.

Implementation Method 1

Enzymes can help break these soils down

Methodology Applied
Scientific EffectEnzyme catalysis: Enzyme

Implementation Method 2

a surfactant, wherein the surfactant is a nonionic surfactant, amphoteric surfactant, or mixtures thereof

Methodology Applied
Scientific EffectSurface tension reduction: Surfactant

Data Source

PatentUS12351783B2Solid enzymatic detergent compositions and methods of use and manufacture
Publication Date: 2025.07.08 ECOLAB USA INC
  • US12351783B2 patent drawing
  • US12351783B2 patent drawing
  • US12351783B2 patent drawing

AI summary

The present disclosure relates to a solid, enzymatic detergent compositions and methods of making and using the same. In a preferred embodiment, the detergent compositions are particularly useful for cleaning medical and dental instruments. In a preferred embodiment the compositions are particularly use for cleaning ware.