Solid Enzyme Formulations with Hydrophobic Coating for Feed
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Solution Overview
Problem
Existing solid enzyme compositions face challenges in achieving uniform and reproducible distribution in animal feed and food products, especially when highly concentrated, due to high enzyme stability requirements and processing difficulties such as dusting and flow issues.
Innovation Solution
A solid enzyme formulation comprising a mixture of salt-stabilized enzyme compositions, particulate carriers, and hydrophobic liquids, which are processed through spray drying and agglomeration to achieve high segregation stability, low dusting, and excellent flow behavior.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If highly concentrated solid enzyme compositions are used, then enzyme activity is sufficient with small dosages, but uniform distribution in feed becomes difficult to achieve
Solution Approach 1:
The enzyme composition is divided into small individual particles through spray drying, creating a segmented structure that facilitates uniform distribution. The enzyme solution is atomized into droplets that dry into discrete particles, preventing clumping and enabling even dispersion in feed matrices.
Solution Approach 2:
The physical state of the enzyme is changed from liquid solution to solid particles through controlled drying. This parameter change from liquid to solid phase, combined with controlling particle size distribution, enables the enzyme to be dosed in small amounts while maintaining uniform distribution properties.
2Reliability
If salt stabilizers are added to maintain enzyme stability, then enzyme activity is preserved, but processing properties such as flow behavior deteriorate
Solution Approach 1:
The addition of salt stabilizers changes the physical parameters of the enzyme solution, including ionic strength and viscosity. By controlling the concentration and type of salt, and by optimizing the drying process parameters, the formulation achieves a balance where enzyme stability is maintained while flow properties remain acceptable for processing.
3Reliability
If spray drying is used to produce solid enzyme compositions, then enzyme stability is improved, but dusting increases and handling becomes difficult
Solution Approach 1:
A binder substance is introduced as an intermediary component during the spray drying process. This binder acts as a mediator that binds particles together, reducing dust generation while maintaining the stability benefits of spray-dried enzyme particles. The binder creates agglomerates that are less prone to airborne dust formation.
Solution Approach 2:
The final product is a composite material consisting of enzyme particles, binder, and potentially other excipients. This composite structure combines the stability advantages of spray-dried enzyme with the handling advantages of bound agglomerates, reducing dusting while preserving enzyme activity.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The resulting formulations exhibit improved handling properties, reduced dusting, and uniform distribution, ensuring effective enzyme activity in animal feed and food products with enhanced processing characteristics.
Implementation Method 1
spray drying liquid enzyme solutions
Implementation Method 2
mixing a particulate, salt-stabilized enzyme composition, a particulate carrier and a hydrophobic liquid
Data Source
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AI summary
The present invention relates to novel solid enzyme formulations comprising mixtures of at least one salt-stabilized enzyme composition, at least one particulate support and at least one hydrophobic fluid. The invention furthermore relates to processes for the preparation of such solid enzyme formulations, and to animal feeds, foodstuffs and food supplements containing such enzyme formulations.