Solid Food Composition for Metabolic Disease Treatment

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Solution Overview

Problem

Current treatments for gestational diabetes mellitus and obesity lack effective, natural, and simple solutions that can provide long-term metabolic benefits and reduce inflammation, particularly in the context of pre-diabetic states and gestational diabetes mellitus.

Innovation Solution

A solid food composition comprising 3-14% protein, 8-22% lipid, and 35-80% complex carbohydrate, with reduced phytic acid and lectin content, manufactured by treating cereal grains, incorporating beta-glucans, and processed to minimize Advanced Glycation End Products, which activates incretins and improves gut health.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If pharmacological compounds are used to treat diabetes, then glucose control is achieved, but the treatment becomes complex and requires strict medication adherence

Engineering Contradiction:
Improveglucose controlVSAvoidtreatment complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent extracts the active beneficial components from complex pharmacological formulations and concentrates them into specific food ingredients (oats, barley, legumes, nuts, seeds, vegetables, fruits) that naturally contain GLP-1 and other metabolic regulators, simplifying the treatment approach while maintaining glucose control effectiveness

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The food-based treatment system enables the body to self-regulate glucose metabolism through natural ingestion of metabolically active foods, eliminating the need for external pharmacological intervention and complex medication management protocols

Inventive Principle:
Principle #25Self-service

2Ease of operation

If natural food-based preload treatment is used, then treatment simplicity and safety are improved, but the effectiveness and speed of glucose control may be reduced

Engineering Contradiction:
Improvetreatment simplicityVSAvoidglucose control effectiveness
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The patent incorporates pre-formed GLP-1 peptides and other metabolic regulators directly into the food matrix before consumption, ensuring that the biologically active components are already prepared and ready to exert their glucose-controlling effects upon ingestion, thereby maintaining rapid and effective glucose control while keeping the treatment simple and natural

Inventive Principle:
Principle #10Preliminary action

3Ease of manufacture

If conventional food processing is used, then manufacturing simplicity is maintained, but phytic acid and lectins remain at high levels causing metabolic issues

Engineering Contradiction:
Improveprocessing simplicityVSAvoidphytic acid and lectin content
Core Design Contradiction:
Ease of manufactureVSObject-affected harmful factors

Solution Approach 1:

The patent applies preliminary treatment steps including soaking, sprouting, fermentation, or enzymatic degradation before food processing and consumption, which pre-reduces phytic acid and lectin levels in the ingredients, thereby lowering harmful factors while maintaining relatively simple manufacturing processes

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent converts the potentially harmful phytic acid and lectins into beneficial forms through controlled processing methods that degrade these anti-nutrients while preserving the nutritional and metabolic benefits of the whole foods, transforming harmful factors into beneficial components

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

4Quantity of substance

If high phytic acid content is maintained in the diet, then nutrient availability is reduced, but processing complexity increases to reduce phytic acid

Engineering Contradiction:
Improvenutrient availabilityVSAvoidprocessing complexity
Core Design Contradiction:
Quantity of substanceVSDevice complexity

Solution Approach 1:

The patent applies preliminary food preparation methods such as soaking, sprouting, or fermentation before consumption, which pre-degrade phytic acid and improve mineral bioavailability, thereby increasing nutrient availability without requiring complex industrial processing

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent utilizes changes in physical and chemical parameters during food preparation (water activity, temperature, time, pH) to modulate phytic acid degradation and enhance nutrient availability, achieving improved mineral absorption through controlled parameter changes rather than complex processing

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition effectively reduces blood glucose levels, enhances satiety, improves metabolic health, and decreases inflammation, offering a natural alternative to pharmacological treatments for gestational diabetes mellitus and obesity.

Implementation Method 1

the complex carbohydrate has been treated to comprise a reduced amount of phytic acid compared to the untreated carbohydrate

Methodology Applied
Scientific EffectPhytic acid reduction:

Implementation Method 2

The preload activates the gastro-intestinal (GI) system and this includes the release of incretins such as glucagon-like peptide-1 (GLP-1). The preload activated GI signals will in turn activate insulin, the main hormone required for glucose uptake in cells.

Methodology Applied
Scientific EffectIncretin activation:

Implementation Method 3

Subjecting said grains to a step of heat treatment

Methodology Applied
Scientific EffectHeat treatment: Heat Treatment

Implementation Method 4

treatment with preload leads to long-term effects thanks to its ability to reduce inflammation, alter the gastro-intestinal microflora and enhance the gut barrier function

Methodology Applied
Scientific EffectGut microbiota modulation:

Data Source

PatentUS20220202050A1Solid food composition
Publication Date: 2022.06.30 GLOOBE PTE LTD
  • US20220202050A1 patent drawing
  • US20220202050A1 patent drawing
  • US20220202050A1 patent drawing

AI summary

The present invention relates to a solid food composition which is generally gluten and lactose free, and its use for treating and preventing metabolic diseases.