Solid-Fuel Heating Unit for Sub-Second Drug Vaporization

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Solution Overview

Problem

There is a need for a device capable of rapid heat production, achieving temperatures within seconds and fractions of seconds, suitable for use in articles intended for human use, as existing self-heating methods are slow and inefficient, particularly in small portable devices.

Innovation Solution

A self-contained heating unit with a thin layer of solid fuel, typically comprising a metal reducing agent and a metal-containing oxidizing agent, disposed on a thermally conductive substrate, which undergoes an exothermic oxidation-reduction reaction to rapidly heat the substrate surface to temperatures above 200°C, facilitated by an igniter system.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If ohmic heating is used in small portable devices, then precise control of energy applied is achieved, but heating time is delayed by seconds or minutes and device size becomes bulky

Engineering Contradiction:
Improvecontrol of energy appliedVSAvoidheating time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent changes the heating mechanism from ohmic heating to combustion of a solid fuel composition. This parameter change enables rapid heating (achieving maximum temperature in less than 1 second) while maintaining precise control through the design of the fuel composition and combustion chamber. The solid fuel composition includes specific ratios of metal powder, oxidizer, and binder that control the combustion rate and temperature profile.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent extracts the heating function from a bulky battery-powered ohmic heating system to a compact solid fuel combustion system. By removing the battery and electrical components, the device achieves rapid heating without the time delays and bulk associated with ohmic heating, while the solid fuel composition provides the necessary energy density in a compact form.

Inventive Principle:
Principle #2Taking out (Extraction)

2Temperature

If exothermic chemical reaction is used for heating, then heat production is mild and suitable for food and drink, but heating speed is slow and cannot achieve rapid temperature increase

Engineering Contradiction:
Improveheat production levelVSAvoidheating speed
Core Design Contradiction:
TemperatureVSSpeed

Solution Approach 1:

The patent changes the chemical reaction type from mild exothermic reactions (suitable for food heating) to controlled combustion reactions. The solid fuel composition uses metal powder (e.g., aluminum, magnesium) combined with oxidizers (e.g., potassium perchlorate, ammonium nitrate) in specific ratios to achieve rapid combustion that produces high temperatures (exceeding 200°C) within less than 1 second, while the thin layer application controls the overall heat output.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent applies partial action by using a thin layer (0.001 to 0.030 inches) of solid fuel composition on the substrate. This thin layer provides sufficient heat for rapid heating applications without producing excessive temperatures that would be harmful, achieving the right balance between heating speed and temperature control for drug vaporization.

Inventive Principle:
Principle #16Partial or excessive action

3Speed

If thin layer of solid fuel is used, then rapid heating is achieved within 1 second, but uniformity of temperature across substrate surface becomes challenging

Engineering Contradiction:
Improveheating speedVSAvoiduniformity of temperature
Core Design Contradiction:
SpeedVSManufacturing precision

Solution Approach 1:

The patent applies local quality by designing the solid fuel composition and substrate interaction to ensure uniform heat distribution. The fuel composition is applied as a thin, relatively uniform layer across the substrate surface, and the combustion propagates evenly through this layer, providing consistent temperatures across the heated area. The substrate material and thickness are also optimized to distribute heat uniformly.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The patent uses a thin layer of solid fuel (0.001 to 0.030 inches) that provides just enough fuel for rapid heating without creating excessive temperatures or uneven heat distribution. This controlled amount of fuel ensures complete combustion across the substrate surface within less than 1 second, achieving both rapid heating and temperature uniformity.

Inventive Principle:
Principle #16Partial or excessive action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The heating unit achieves rapid and uniform temperature increase across the substrate surface, with 90% of the area reaching the desired temperature within 1 second of ignition, suitable for applications such as drug vaporization in medical devices.

Implementation Method 1

A self-contained heating unit with a thin layer of solid fuel, typically comprising a metal reducing agent and a metal-containing oxidizing agent, disposed on a thermally conductive substrate, which undergoes an exothermic oxidation-reduction reaction to rapidly heat the substrate surface to temperatures above 200°C

Methodology Applied
Scientific EffectExothermic oxidation-reduction reaction: Exothermic Reaction

Implementation Method 2

A self-contained heating unit with a thin layer of solid fuel, typically comprising a metal reducing agent and a metal-containing oxidizing agent, disposed on a thermally conductive substrate, which undergoes an exothermic oxidation-reduction reaction to rapidly heat the substrate surface to temperatures above 200°C

Methodology Applied
Scientific EffectThermal conduction: Conduction (thermal)

Data Source

PatentUS8387612B2Self-contained heating unit and drug-supply unit employing same
Publication Date: 2013.03.05 ALEXZA PHARMACEUTICALS INC
  • US8387612B2 patent drawing
  • US8387612B2 patent drawing
  • US8387612B2 patent drawing

AI summary

Heating units, drug supply units and drug delivery articles capable of rapid heating are disclosed. Heating units comprising a substrate and a solid fuel capable of undergoing an exothermic metal oxidation reaction disposed within the substrate are disclosed. These heating units can be actuated by electrical resistance, by optical ignition or by percussion. Drug supply units and drug delivery articles wherein a solid fuel is configured to heat a substrate to a temperature sufficient to rapidly thermally vaporize a drug disposed thereon are also disclosed.