Substantially Solid Solution for Targeted Subcutaneous Fat Reduction

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Solution Overview

Problem

Current methods for reducing subcutaneous fat, such as invasive surgeries and topical cryolipolysis, are invasive, painful, and lack precision, with limitations in depth and uniformity of fat removal, particularly targeting deep subcutaneous adipose tissue effectively.

Innovation Solution

A substantially solid solution comprising 71% to 100% frozen water, optionally with additives like salts and thickeners, is administered to treat subcutaneous adipose tissue layers, allowing for precise and targeted fat reduction through cryolipolysis, with the solution being injected or applied in various patterns to achieve desired aesthetic outcomes.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If invasive fat reduction procedures (liposuction, surgery) are used, then fat removal effectiveness is improved, but patient safety and comfort deteriorate due to risks of infection, scarring, pain, and recovery time

Engineering Contradiction:
Improvefat removal effectivenessVSAvoidpatient safety and comfort
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

The patent replaces mechanical fat removal methods (suction, surgical excision) with a chemical-biological approach using deoxycholic acid injection. The acid chemically disrupts adipocyte membranes, causing cell death and natural elimination, thereby eliminating the need for mechanical trauma and associated surgical risks

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent introduces deoxycholic acid as an intermediary substance that mediates fat cell destruction. This chemical intermediary selectively targets adipocytes without affecting surrounding tissues, enabling precise fat removal while avoiding the harmful effects of direct mechanical intervention

Inventive Principle:
Principle #24Intermediary (Mediator)

2Object-affected harmful factors

If minimally invasive procedures (laser, radio frequency, ultrasound) are used, then patient safety is improved compared to surgery, but treatment precision and uniformity deteriorate

Engineering Contradiction:
Improvepatient safetyVSAvoidtreatment precision and uniformity
Core Design Contradiction:
Object-affected harmful factorsVSManufacturing precision

Solution Approach 1:

The patent applies local quality by injecting deoxycholic acid directly into specific fat deposits through precise injection techniques. The treatment is localized to exact treatment zones, ensuring uniform chemical exposure to target adipocytes while maintaining patient safety through minimal tissue disruption

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The patent changes the physical-chemical parameters of the treatment by using a chemical agent (deoxycholic acid) with specific properties that disrupt adipocyte membranes. This chemical approach provides more predictable and uniform results compared to variable energy-based methods, improving treatment precision while maintaining safety

Inventive Principle:
Principle #35Parameter changes

3Object-affected harmful factors

If topical cryolipolysis is used, then non-invasiveness is improved, but treatment depth and effectiveness deteriorate due to limited penetration through skin

Engineering Contradiction:
ImproveinvasivenessVSAvoidtreatment depth
Core Design Contradiction:
Object-affected harmful factorsVSLength of stationary object

Solution Approach 1:

The patent uses deoxycholic acid as a chemical intermediary that can be delivered directly to the target depth via injection, bypassing the skin barrier limitation of topical methods. This allows effective treatment of deep subcutaneous fat while maintaining minimal invasiveness

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent employs injection technology to deliver the treatment solution directly to the target tissue depth, using fluid dynamics to achieve precise placement. This overcomes the depth limitation of topical applications by delivering the active agent directly where needed, regardless of fat layer depth

Inventive Principle:
Principle #29Pneumatics and hydraulics

4Manufacturing precision

If deoxycholic acid injection is used, then treatment precision is improved, but potential harmful effects may increase due to chemical delivery into the body

Engineering Contradiction:
Improvetreatment precisionVSAvoidchemical delivery risks
Core Design Contradiction:
Manufacturing precisionVSObject-affected harmful factors

Solution Approach 1:

The patent optimizes the concentration and formulation parameters of deoxycholic acid to achieve effective fat cell disruption while minimizing adverse effects. By carefully controlling these parameters, the treatment maintains high precision while reducing chemical delivery risks

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent ensures the chemical agent is delivered locally to specific treatment zones with precise injection techniques. This localized delivery minimizes systemic exposure and reduces potential harmful effects while maintaining high treatment precision at the target site

Inventive Principle:
Principle #3Local quality

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The method provides a non-invasive, precise, and effective means for reducing subcutaneous fat, particularly deep layers, with improved cosmetic results and reduced risk of complications compared to traditional methods, by utilizing a high ice coefficient solution that selectively targets and removes adipocytes.

Implementation Method 1

The present invention provides methods for treatment and removal of subcutaneous fat by administering a substantially solid solution to a subject for fat reduction

Methodology Applied
Scientific EffectCryolipolysis: Freezing

Implementation Method 2

A substantially solid solution comprising 71% to 100% frozen water

Methodology Applied
Scientific EffectFreezing: Freezing

Data Source

PatentUS20230031549A1Substantially solid solution, systems and methods for generating a substantially solid solution, and methods of administration thereof
Publication Date: 2023.02.02 MIRAKI INNOVATION THINK TANK LLC
  • US20230031549A1 patent drawing
  • US20230031549A1 patent drawing
  • US20230031549A1 patent drawing

AI summary

A substantially solid solution is provided, which includes water and optionally one or more additives, wherein about 71% to about 100% of the water by volume is in a solid state. The substantially solid solution may be administered to a subcutaneous fat layer of a subject, in order to reduce or remove adipocytes through freezing. The substantially solid solution may be generated in a mold, or at a point of delivery, and may be administered by any suitable device or administered directly to a treatment site via an incision.