Solid State Fermentation Plant with Transparent Bags

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Solution Overview

Problem

Existing solid state fermentation technologies face challenges in maintaining sterility, operational complexity, and high costs due to complex structures and lack of visual control, which affects the productivity and reliability of microorganism culture production.

Innovation Solution

A multifunctional solid state fermentation plant with a simplified structure featuring transparent, autoclave plastic bags on a scaffolding system for sterility and temperature control, an automatic inoculum injection device, and a system for controlled air flow and sterilization, allowing for visual monitoring and reduced operation costs.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If complex structures with multiple chambers and filters are used in fermentation bags, then sterility control is improved, but device complexity increases and operation costs rise

Engineering Contradiction:
Improvesterility controlVSAvoidstructure complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent removes the complex internal subdivision elements (diaphragms, multiple filters, nozzles) from the fermentation bag, retaining only the essential function of sterility control through a simplified single-chamber design with external filter connection, thereby reducing device complexity while maintaining sterility reliability

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent employs disposable fermentation bags with integrated filter units that can be sterilized and discarded after use, eliminating the need for complex reusable structures with multiple components, thus reducing both device complexity and operation costs while ensuring sterility

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

2Reliability

If closed structure fermenters with multiple plates are used, then sterility is maintained, but visual control capability is lost and pollution detection becomes difficult

Engineering Contradiction:
Improvesterility maintenanceVSAvoidvisual control capability
Core Design Contradiction:
ReliabilityVSDifficulty of detecting and measuring

Solution Approach 1:

The patent uses transparent plastic fermentation bags that allow visual observation of the fermentation process while maintaining sterility through their sealable structure, enabling both visual control and sterility maintenance simultaneously without requiring complex transparent windows or observation ports

Inventive Principle:
Principle #30Flexible shells and thin films

Solution Approach 2:

The transparent bag structure provides continuous visual feedback on the fermentation state and potential contamination, allowing operators to detect and respond to pollution events immediately, thereby maintaining sterility through active monitoring while preserving visual control capability

Inventive Principle:
Principle #23Feedback

3Productivity

If liquid phase fermentation apparatus with swinging platforms is used, then mixing is improved, but applicability to solid state fermentation is reduced and structural complexity increases

Engineering Contradiction:
Improvemixing efficiencyVSAvoidapplicability to solid state fermentation
Core Design Contradiction:
ProductivityVSAdaptability or versatility

Solution Approach 1:

The patent designs a simple horizontal bag structure that can be adapted for both liquid phase and solid state fermentation by changing the substrate type and aeration method, eliminating the need for complex swinging platforms while maintaining versatility across different fermentation modes through basic structural simplicity

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent uses controlled air flow through the horizontal bag to achieve mixing and substrate aeration in solid state fermentation, replacing mechanical swinging platforms with pneumatic action, thereby improving adaptability to solid state fermentation while maintaining productivity through effective gas-solid contact

Inventive Principle:
Principle #29Pneumatics and hydraulics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The plant achieves high productivity, absolute sterility, and low investment costs by ensuring sterility and visual control, while maintaining efficient temperature and air flow management, enhancing the production of microorganisms and secondary metabolites.

Implementation Method 1

said shelves (1), in variable number, depending on the plant size, that are provided with an interspace or a coil wherein a thermostabilizing fluid is made to flow, so to thermostabilize, contemporarily, the bag (7)

Methodology Applied
Scientific EffectHeat conduction: Conduction (thermal)

Implementation Method 2

by the steam autoclave (24) for the sterilization ad cooking, if any, when substrata are used that need to be cooked

Methodology Applied
Scientific EffectSteam sterilization: Heating

Implementation Method 3

said series of filter (15) for sterilized air being formed by a metallic container with a replaceable sterilizing cartridge (16)

Methodology Applied
Scientific EffectFiltration: Filter (physical)

Implementation Method 4

by the automatic device or gun (26) for the inoculum injection, in an automatically predetermined quantity, into the hermetically closed bag (7)

Methodology Applied
Scientific EffectPressure-driven flow: Pressure Gradient

Implementation Method 5

a pump for the delivery of said fluid to the shelves (1); by control and regulation instruments and by suitable distribution and return manifolds of said fluid

Methodology Applied
Scientific EffectHeat exchange: Heat Exchanger

Implementation Method 6

wherein a thermostabilizing fluid is made to flow, so to thermostabilize, contemporarily, the bag (7)

Methodology Applied
Scientific EffectConvection cooling: Convection

Data Source

PatentEP2505634B1A solid state fermentation plant
Publication Date: 2013.12.04 TECHNELEP
  • EP2505634B1 patent drawingFigure 1~3
  • EP2505634B1 patent drawingFigure 4~5

AI summary

A solid state fermentation plant for the production of vital microorganism cultures in sterile conditions and with high concentration is described. Said plant, in comparison with other similar plants and known devices, is characterized by a remarkable structural simplicity and a high reliability.