Solid-State Multi-Well Plate Reader With Temporary Optical Alignment

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Solution Overview

Problem

Existing plate readers are large, complex, and costly, requiring dedicated laboratory space, are difficult to integrate into specialized environments, and incur high maintenance costs, with limited availability in a single lab leading to resource bottlenecks.

Innovation Solution

A solid-state, multi-well plate reader with temporarily alignable emitter and receptor assemblies using two alignment trays, allowing for reproducible optical alignment and easy access, while blocking ambient light interference.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Volume of moving object

If traditional plate readers use fixed-position emitters and detectors with complex optical systems, then measurement precision is maintained, but device size becomes large and requires dedicated laboratory space

Engineering Contradiction:
Improvedevice sizeVSAvoidoptical alignment precision
Core Design Contradiction:
Volume of moving objectVSMeasurement precision

Solution Approach 1:

The patent makes the emitter and detector assemblies movable rather than fixed, allowing them to be temporarily aligned during measurement and repositioned for storage. The alignment trays enable dynamic positioning that maintains measurement precision while reducing the device's permanent footprint.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The device is divided into separate alignment trays that can be independently positioned. The emitter assembly and detector assembly are segmented from the main device body, allowing them to be temporarily aligned only when needed for measurement, thereby reducing the required device volume.

Inventive Principle:
Principle #1Segmentation

2Adaptability or versatility

If traditional plate readers use complex optical systems with monochromators and filters, then measurement capability is comprehensive, but device complexity increases and maintenance costs rise

Engineering Contradiction:
Improvemeasurement capabilityVSAvoidoptical system complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent extracts the complex optical components (monochromators, filters) from the device, relying instead on the inherent optical properties of the emitters and detectors. This simplifies the optical system while maintaining measurement versatility through the use of multiple emitter types and detector configurations.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent replaces complex mechanical optical systems with solid-state emitters and detectors. The alignment trays provide mechanical positioning, but the measurement function is achieved through electronic detection rather than complex optical mechanics, reducing overall device complexity.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Adaptability or versatility

If traditional plate readers are designed as permanently fixed instruments, then measurement stability is ensured, but adaptability to specialized environments such as incubators or anaerobic chambers is lost

Engineering Contradiction:
Improveenvironmental adaptabilityVSAvoidmeasurement stability
Core Design Contradiction:
Adaptability or versatilityVSReliability

Solution Approach 1:

The movable alignment trays allow the device to be dynamically configured for different environments. The emitter and detector assemblies can be temporarily positioned for stable measurements and then repositioned, enabling the device to adapt to various environments including incubators and anaerobic chambers while maintaining measurement reliability during operation.

Inventive Principle:
Principle #15Dynamics

4Reliability

If traditional plate readers use expensive service contracts and specialized maintenance, then measurement reliability is maintained, but operational cost increases and downtime increases

Engineering Contradiction:
Improvemeasurement reliabilityVSAvoidmaintenance accessibility
Core Design Contradiction:
ReliabilityVSEase of repair

Solution Approach 1:

The simplified solid-state design with movable alignment trays enables users to perform basic maintenance and troubleshooting themselves without requiring specialized service contracts. The modular construction allows easy access to components for cleaning and inspection, improving ease of repair while maintaining measurement reliability.

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables precise optical measurements in a compact, flexible, and cost-effective format, suitable for various environments and reducing maintenance needs.

Implementation Method 1

an emitter assembly (4) having a plurality of emitters

Methodology Applied
Scientific EffectLight emission: Light Emitting Diode

Implementation Method 2

a receptor assembly (5) having a plurality of receptors

Methodology Applied
Scientific EffectLight detection: Photoelectric Effect

Data Source

PatentUS12403475B2Solid-state, multi-well plate reader
Publication Date: 2025.09.02 CERILLO INC
  • US12403475B2 patent drawing
  • US12403475B2 patent drawing
  • US12403475B2 patent drawing

AI summary

The present invention generally relates to a solid-state, multi-well plate reader including an emitter assembly having a plurality of emitters and a receptor assembly having a plurality of receptors, where the positions of these assemblies are not fixed relative to each other but are temporarily aligned for measurement by way of two alignment trays.