Solidago Extract Composition for Diabetic Periodontitis Treatment

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Solution Overview

Problem

Current mouth and tooth care compositions containing medicinal herb extracts are ineffective in treating existing periodontitis, particularly diabetic periodontitis, and often come with unfavorable side effects from long-term antibiotic treatments.

Innovation Solution

A pharmaceutical composition is prepared using an extract of a Solidago species, specifically the solid residue after solvent removal, which is used as an active agent to treat diabetic periodontitis, offering an alternative to antibiotics with reduced side effects.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If antibiotic treatment is used for diabetic periodontitis, then the periodontal disease is treated, but unfavorable side effects occur

Engineering Contradiction:
Improvetreatment effectivenessVSAvoidside effects
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent replaces long-term antibiotic treatment with a herbal extract composition that provides effective treatment without the harmful side effects of antibiotics, offering a safer alternative that maintains treatment effectiveness while eliminating adverse effects

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Solution Approach 2:

The patent introduces a herbal extract composition as an intermediary substance between the patient and the periodontal infection, providing therapeutic action through natural compounds rather than synthetic antibiotics, thus mediating the treatment process without the harmful side effects

Inventive Principle:
Principle #24Intermediary (Mediator)

2Object-affected harmful factors

If mouth and tooth care compositions containing medicinal herb extracts are used, then gingivitis is reduced, but existing periodontitis is not effectively treated

Engineering Contradiction:
Improvegingivitis reductionVSAvoidperiodontitis treatment effectiveness
Core Design Contradiction:
Object-affected harmful factorsVSReliability

Solution Approach 1:

The patent modifies the composition parameters by using a specific herbal extract (Solidago) with standardized active ingredients at defined concentrations, transforming the composition from a general gingivitis treatment to an effective periodontitis treatment while maintaining safety

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent creates a composite herbal extract composition containing multiple active ingredients from Solidago species, combining their synergistic effects to achieve both gingivitis reduction and effective periodontitis treatment that single-herb compositions cannot accomplish

Inventive Principle:
Principle #40Composite materials

Data Source

PatentEP1945236B1A composition for the treatment of diabetic periodontitis
Publication Date: 2009.04.01 KERI AGNES

AI summary

The invention refers to the use of an extract of a part of a Solidago species, wherein said part has grown above the earth, or the solid residue remaining after the removal of the solvent content of the extract as the active agent for the preparation of a pharmaceutical composition suitable for the treatment of diabetic periodontitis.