Soluble Membrane Valve for Automated Supernatant Drainage

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Manual removal of supernatant from centrifuged liquid samples is cumbersome and inefficient, requiring manual intervention with pipettes.

Innovation Solution

A device with a holding chamber and a valve device featuring a soluble membrane that automatically opens to allow controlled drainage of supernatant, either by pressure or dissolution, facilitating automated removal without manual intervention.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If manual removal of supernatant using a pipette is used, then the supernatant can be separated from the centrifuged sample, but the process becomes cumbersome and requires manual intervention

Engineering Contradiction:
Improveease of supernatant removalVSAvoiddevice complexity
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

The valve device automatically opens to drain the supernatant without requiring manual intervention with a pipette. The system serves itself by using the dissolved membrane as the opening mechanism, eliminating the need for external manual operation while maintaining simple device structure.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The manual mechanical operation of using a pipette to remove supernatant is replaced by an automatic valve mechanism. The valve opens in response to the dissolved membrane, substituting the manual mechanical process with an automated system that is equally simple in structure.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Extent of automation

If automated drainage is implemented, then manual intervention is eliminated, but the device structure becomes more complex

Engineering Contradiction:
Improveautomation of supernatant removalVSAvoiddevice complexity
Core Design Contradiction:
Extent of automationVSDevice complexity

Solution Approach 1:

The valve device achieves automation through self-service mechanism where the dissolved membrane directly causes the valve to open. The system uses its own operational process (membrane dissolution) to trigger the automation, eliminating the need for external control systems or complex automation mechanisms.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The valve device utilizes parameter changes in the membrane (from intact to dissolved state) to trigger automation. This chemical parameter change naturally drives the mechanical opening of the valve, achieving automation through material property transformation rather than complex control systems.

Inventive Principle:
Principle #35Parameter changes

3Productivity

If a temporarily closed outlet is used, then controlled drainage is enabled, but the valve mechanism adds structural complexity

Engineering Contradiction:
Improveefficiency of sample processingVSAvoidvalve device structure
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The valve device structure is minimized by using parameter changes in the membrane (intact to dissolved) to control the opening. This approach achieves controlled drainage efficiency through material transformation rather than complex mechanical valve structures, maintaining simplicity while enabling productivity.

Inventive Principle:
Principle #35Parameter changes

4Loss of time

If manual pipetting is used for supernatant removal, then the process is simple in structure, but it requires time-consuming manual handling

Engineering Contradiction:
Improvetime for supernatant removalVSAvoidease of sample manipulation
Core Design Contradiction:
Loss of timeVSEase of operation

Solution Approach 1:

The system eliminates time-consuming manual handling by implementing self-service automation. The valve automatically opens when the membrane dissolves, enabling the system to perform supernatant removal without human intervention, thus saving time while maintaining operational simplicity.

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables simplified and automated manipulation of liquid samples by allowing controlled drainage of supernatant, reducing manual handling and improving efficiency in concentrating solid constituents for further examination.

Implementation Method 1

the valve device opens automatically as a result of the membrane being partially or completely dissolved by the liquid

Methodology Applied
Scientific EffectDissolution: Solvation

Implementation Method 2

the sample is centrifuged in the holding chamber and then drained off from the holding chamber—particularly by centrifugal and/or gravitational force—through an outlet

Methodology Applied
Scientific EffectCentrifugal force: Centrifugal Force

Implementation Method 3

the sample is centrifuged in the holding chamber and then drained off from the holding chamber—particularly by centrifugal and/or gravitational force—through an outlet

Methodology Applied
Scientific EffectGravity: Gravitation

Data Source

PatentUS9221049B2Device and method for removing a supernatant of a liquid sample, and use of a valve device having a soluble membrane
Publication Date: 2015.12.29 BOEHRINGER INGELHEIM MICROPARTS GMBH
  • US9221049B2 patent drawing
  • US9221049B2 patent drawing

AI summary

A device and a method for separating a supernatant of a liquid sample are proposed, in which an outlet is closed off by a water-soluble membrane that dissolves after a certain length of time so that the supernatant of the sample is automatically drained away after centrifugation. The water-soluble membrane may in principle may also be used for other purposes for temporarily retaining a liquid in a holding chamber.