Solute Concentration Measurement Device with Filter Membrane

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Solution Overview

Problem

Current methods are inadequate for accurately and efficiently determining the concentration of solutes, such as glucose, in body fluids in real-time for medical monitoring, particularly in maintaining long-term implantability and precise fluid communication with body fluids.

Innovation Solution

A solute concentration measurement device comprising a filter membrane, exchange chamber, separator, and sensor, which allows selective diffusion of solvent and measures conditions within the device to calculate solute concentration, maintaining fluid communication with body fluids and enabling real-time monitoring.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If a filter membrane is used to provide selective fluid communication between the sample solution and the exchange chamber, then the device can achieve real-time monitoring of solute concentration, but the device complexity increases due to the need for selective permeability and controlled diffusion

Engineering Contradiction:
Improvereal-time monitoring capabilityVSAvoiddevice complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The device is divided into distinct functional chambers: an exchange chamber for selective solvent diffusion and a sensing chamber for concentration measurement. The filter membrane separates these chambers and enables controlled interaction between the sample solution and exchange chamber, allowing real-time monitoring while managing complexity through functional segmentation.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The filter membrane acts as an intermediary between the sample solution and the exchange chamber, enabling selective fluid communication. It allows solvent molecules to pass through while blocking solute molecules, facilitating controlled diffusion and concentration equilibrium without requiring direct contact between the sample and sensing components.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If the device maintains fluid communication with body fluids for accurate concentration measurement, then measurement precision is improved, but the reliability of long-term implantability decreases due to potential tissue response and fluid communication stability issues

Engineering Contradiction:
Improveconcentration measurement precisionVSAvoidlong-term implantability
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The device extracts only the necessary function of fluid communication with body fluids while isolating the sensitive sensing components. The filter membrane and chamber structure allow selective interaction with body fluids for accurate concentration measurement, while the separated exchange and sensing chambers protect the internal components from direct exposure to tissue responses, improving long-term reliability.

Inventive Principle:
Principle #2Taking out (Extraction)

3Measurement precision

If the exchange chamber and sensing chamber are separated by a separator, then the measurement precision is improved through controlled diffusion, but the device complexity increases due to additional separation components

Engineering Contradiction:
Improveconcentration measurement precisionVSAvoiddevice complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The device separates the exchange chamber and sensing chamber using a separator, creating distinct functional zones. This segmentation allows controlled diffusion of solvent from the exchange chamber to the sensing chamber while preventing direct mixing, thereby improving measurement precision through controlled mass transfer.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The separator provides localized control over fluid and solute transport between chambers. It allows selective passage of solvent molecules while blocking solute molecules, creating different local environments in each chamber optimized for their specific functions: exchange for diffusion and sensing for measurement.

Inventive Principle:
Principle #3Local quality

4Measurement precision

If the device allows selective diffusion of solvent through the filter membrane, then the concentration measurement accuracy is improved, but the loss of substance increases due to continuous solvent exchange with body fluids

Engineering Contradiction:
Improveconcentration measurement accuracyVSAvoidsolvent loss
Core Design Contradiction:
Measurement precisionVSLoss of substance

Solution Approach 1:

The filter membrane enables continuous selective diffusion of solvent between the exchange chamber and the surrounding body fluids, maintaining a steady state concentration in the sensing chamber. This continuous action allows accurate real-time measurement while the membrane's selectivity minimizes unnecessary solvent loss by allowing only controlled exchange.

Inventive Principle:
Principle #20Continuity of useful action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables real-time monitoring of solute concentrations in body fluids, ensuring accurate and efficient glucose monitoring in medical contexts, with the device being adaptable for both short-term and long-term implantation, maintaining precise fluid communication and minimizing disruption to the body fluid concentration.

Implementation Method 1

The filter membrane may provide selective fluid communication between the sample solution and the exchange chamber

Methodology Applied
Scientific EffectSelective diffusion: Diffusion

Implementation Method 2

allowing selective diffusion of a solvent

Methodology Applied
Scientific EffectOsmosis: Osmosis

Implementation Method 3

The separator may separate the exchange chamber from the sensing chamber and cause a change in a condition of the sensing chamber corresponding to a change of a condition of the exchange chamber

Methodology Applied
Scientific EffectPressure transmission: Pressure Gradient

Data Source

PatentUS9400241B2Solute concentration measurement device and related methods
Publication Date: 2016.07.26 TANDEM DIABETES CARE INC
  • US9400241B2 patent drawing
  • US9400241B2 patent drawing
  • US9400241B2 patent drawing

AI summary

A solute concentration measurement device is disclosed. The device may comprise a filter membrane, an exchange chamber, a sensing chamber, a separator, and a sensor. The device may be configured to be placed in fluid communication with a sample solution containing a solute and a solvent. The filter membrane may provide selective fluid communication between the solution and the exchange chamber. The separator may separate the exchange chamber from the sensing chamber and cause a change in a condition of the sensing chamber corresponding to a change of a condition of the exchange chamber. The sensor may sense the condition pertaining to the sensing chamber and calculate the concentration of the sample solution corresponding to this change.