Solution Blow Spin Device for Simultaneous Cell and Polymer Wound Spraying
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Solution Overview
Problem
Current wound care methods, particularly for burn wounds, face challenges such as leakage of autologous skin cell suspensions (ASCS) during application, poor conformity to irregular wound surfaces, and the need for frequent and painful dressing changes, leading to delayed healing and increased infection risk.
Innovation Solution
A solution blow spin device that simultaneously sprays ASCS and a polymer using a multi-syringe pump assembly and airbrush adapter, allowing for precise and efficient application of biodegradable polymer fibers directly onto the wound, conforming to irregular surfaces and reducing the need for manual handling and adhesives.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If ASCS and dressing application are performed in a stepwise fashion, then the application process is simple and manageable, but the ASCS can leak out of the wound bed
Solution Approach 1:
The patent combines two separate application steps (ASCS application and dressing application) into a single simultaneous operation using a dual-syringe device. The first syringe delivers ASCS while the second syringe delivers polymer dressing material at the same time, preventing ASCS leakage by establishing immediate polymer containment within the wound bed during application.
Solution Approach 2:
The device prepares both ASCS and polymer dressing materials for simultaneous delivery in advance. The syringes are pre-loaded and positioned, with the polymer material ready to be deposited immediately alongside the ASCS, ensuring that the polymer matrix is established concurrently with cell delivery to prevent leakage.
2Ease of operation
If traditional dressing methods are used, then the application is straightforward, but the dressing does not conform well to irregular wound surfaces
Solution Approach 1:
The patent changes the physical state and delivery method of the polymer dressing from pre-formed rigid dressings to a sprayable solution or suspension. By controlling the delivery parameters (pressure, flow rate, spray pattern), the polymer material can conform to irregular wound surfaces while maintaining ease of application through the handheld device.
Solution Approach 2:
The invention transitions from applying pre-formed two-dimensional dressings to delivering a three-dimensional sprayable polymer matrix that can adapt to complex wound geometries. The spray delivery system allows the material to flow and conform to irregular surfaces before setting, achieving better shape adaptation.
3Ease of operation
If manual handling and adhesives are used for dressing application, then the application process is simple, but it causes pain and increases infection risk
Solution Approach 1:
The patent replaces manual mechanical handling and adhesive application with a spray delivery system. The polymer dressing material is delivered through a spray nozzle that atomizes the material onto the wound surface, eliminating the need for manual manipulation, adhesives, and associated pain or infection risks while maintaining operational simplicity.
4Reliability
If frequent dressing changes are performed, then wound monitoring is improved, but healing is delayed and pain increases
Solution Approach 1:
The simultaneous delivery of ASCS and polymer dressing creates a continuous, integrated wound treatment system. The polymer matrix provides ongoing protection and a moist environment, reducing the frequency of dressing changes needed while maintaining effective wound monitoring. The biodegradable polymer gradually breaks down, providing sustained benefits throughout the healing process.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The device streamlines wound care by minimizing ASCS leakage, improving wound conformity, reducing pain, and enhancing healing through customizable, biodegradable dressings that absorb excess exudate and maintain a moist environment, thereby reducing infection and scarring.
Implementation Method 1
a first lead screw mechanically coupled to a first actuator and a second lead screw mechanically coupled to a second actuator
Implementation Method 2
an air channel inlet fluidly coupled to the hollow nozzle body, the air channel inlet configured to receive a pressurized gas, the hollow nozzle body configured to eject the pressurized gas through the first opening around the tip of the first hollow needle
Data Source
AI summary
A solution blow spin device includes a syringe pump assembly, an airbrush adapter, and a handle base. The syringe pump assembly, airbrush adapter, and handle base are reversibly coupled to one another and configured to work in tandem to address wound dressing using a polymer solution and autologous skin cell suspension co-spray. The airbrush adapter includes multiple nozzles for deposition of multiple solutions sequentially or simultaneously in order to improve would dressing efficacy. The syringe pump assembly includes multiple syringes holding the multiple solutions, and the syringes can be emptied by individually addressable lead screws configured to translate blocks to depress syringe plungers when the lead screws are rotated via corresponding actuators.