Solution Jetting Device Backlash Control
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Solution Overview
Problem
Existing biochemical analyzers face challenges in accurately controlling the amount of solution jetted, particularly for small volumes, which can significantly impact analysis performance and accuracy.
Innovation Solution
A solution jetting device and method that utilize a cylindrical member with a movable plunger, drive mechanisms, flow passages, and valves to control the jetting of biological samples or reagents, ensuring the end face of the nozzle is positioned within a specific distance from the solution surface, allowing for precise control of the solution amount jetted.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If a conventional syringe pump is used to jet small volumes of solution (5 ml or less), then the device can deliver the solution, but the amount of solution jetted cannot be controlled with high accuracy due to backlash errors
Solution Approach 1:
The patent applies preliminary action by performing a suck-back operation before the actual jetting. The syringe pump sucks back a predetermined volume of solution into the syringe barrel before jetting, which eliminates backlash errors in the drive mechanism. This preliminary suck-back action ensures that the syringe plunger is firmly engaged with the solution, eliminating play or clearance that would cause inaccurate dosing during the subsequent jetting operation.
Solution Approach 2:
The patent changes the operational parameters of the syringe pump by controlling it to operate in two distinct phases: a suck-back phase where the plunger moves to draw solution into the barrel, and a jetting phase where the plunger moves to eject the solution. By carefully controlling the volume sucked back and the timing of the jetting operation, the system achieves high accuracy in the amount of solution delivered, transforming the unreliable continuous operation into a controlled two-stage process.
2Quantity of substance
If the nozzle is positioned far from the solution surface, then solution adhesion to the nozzle is reduced, but the amount of solution jetted becomes unstable
Solution Approach 1:
The patent applies parameter changes by precisely controlling the vertical position of the nozzle relative to the solution surface in the measurement container. The nozzle is positioned at a specific height range where the distal end is submerged in the jetted solution by a controlled amount (0.5-2.0 mm). This optimized positioning parameter simultaneously achieves stable solution delivery and minimizes harmful adhesion, resolving the contradiction between these two requirements.
Solution Approach 2:
The patent applies partial action by having the nozzle distal end partially submerged in the solution rather than completely above or completely below the surface. This partial submersion (0.5-2.0 mm) is the optimal amount that provides enough contact for stable jetting while limiting excessive contact that would cause harmful adhesion. The suck-back volume is also set to a partial amount that is sufficient to eliminate backlash but not so large as to waste solution.
3Quantity of substance
If the nozzle is positioned deep in the solution, then solution adhesion stabilizes the jetted amount, but excessive solution remains on the nozzle forming droplets
Solution Approach 1:
The patent applies parameter changes by optimizing the nozzle submersion depth to a specific range (0.5-2.0 mm). This precise parameter setting ensures that the nozzle distal end is enough submerged to stabilize the jetted solution amount through controlled adhesion, while not being so deep that excessive solution accumulates and forms droplets on the nozzle. The parameter is carefully chosen to balance these competing effects.
Solution Approach 2:
The patent applies partial action by having the nozzle distal end partially submerged rather than fully immersed. This partial submersion (0.5-2.0 mm) provides just enough contact with the solution to stabilize the jetting process and control adhesion, while limiting the contact area to prevent excessive solution accumulation that would form droplets. The suck-back volume is also set to a partial amount sufficient for eliminating backlash without causing excessive solution retention.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach enhances analysis performance by accurately controlling the amount of solution jetted, minimizing errors caused by syringe pump backlash and ensuring consistent solution delivery, even for small volumes of 5 ml or less.
Implementation Method 1
jets the solution into the measurement container from a nozzle connected to the hole portion of the syringe by moving the plunger in a direction in which the volume of the hollow portion is reduced
Implementation Method 2
controls the surface of a solution, which is jetted to the measurement container, and the end face of the nozzle to the same height in a case in which the jet of a solution ends. Accordingly, the biochemical analyzer prevents a solution from remaining on the distal end of the nozzle in the form of a droplet
Data Source
AI summary
A solution jetting device includes: a cylindrical member; a movable member that is movably fitted to a hollow portion of the cylindrical member; a first drive mechanism that moves the movable member; a first flow passage that connects a solution container, in which a solution containing a biological sample or containing a reagent to be reacted with a biological sample is contained, to the hollow portion; an openable and closable first on-off valve that is provided on the first flow passage; a jetting tool that jets the solution to an objective region; a second flow passage that connects the hollow portion to the jetting tool; an openable and closable second on-off valve that is provided on the second flow passage; a second drive mechanism as defined herein; and a control unit as defined herein.


